ENSMUSG00000029860


Mus musculus

Features
Gene ID: ENSMUSG00000029860
  
Biological name :Zyx
  
Synonyms : Q62523 / Zyx / zyxin
  
Possible biological names infered from orthology : Q15942
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: B2.1
Gene start: 42349630
Gene end: 42360213
  
Corresponding Affymetrix probe sets: 10537770 (MoGene1.0st)   1417240_at (Mouse Genome 430 2.0 Array)   1438552_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000145052
Ensembl peptide - ENSMUSP00000145189
Ensembl peptide - ENSMUSP00000145451
Ensembl peptide - ENSMUSP00000145236
Ensembl peptide - ENSMUSP00000070427
Ensembl peptide - ENSMUSP00000126622
Ensembl peptide - ENSMUSP00000144863
NCBI entrez gene - 22793     See in Manteia.
MGI - MGI:103072
RefSeq - NM_001289619
RefSeq - XM_006505936
RefSeq - NM_011777
RefSeq - NM_001289617
RefSeq - NM_001289618
RefSeq Peptide - NP_001276546
RefSeq Peptide - NP_001276547
RefSeq Peptide - NP_001276548
RefSeq Peptide - NP_035907
swissprot - Q7TQE2
swissprot - A0A0N4SVD2
swissprot - A0A0N4SUX7
swissprot - A0A0N4SVP4
swissprot - Q62523
Ensembl - ENSMUSG00000029860
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zyxENSDARG00000075733Danio rerio
 ZYXENSGALG00000014688Gallus gallus
 ZYXENSG00000159840Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lpp / Q8BFW7 / Lipoma-preferred partner homolog / Q93052* / LIM domain containing preferred translocation partner in lipoma*ENSMUSG0000003330638
Trip6 / Q9Z1Y4 / thyroid hormone receptor interactor 6 / Q15654*ENSMUSG0000002334830
Limd1 / Q9QXD8 / LIM domain-containing protein 1 / Q9UGP4* / LIM domains containing 1*ENSMUSG0000002523925
Fblim1 / Q71FD7 / Filamin-binding LIM protein 1 / Q8WUP2*ENSMUSG0000000621923
Ajuba / Q91XC0 / LIM domain-containing protein ajuba / Q96IF1* / ajuba LIM protein*ENSMUSG0000002217822
Wtip / Q7TQJ8 / WT1-interacting protein / A6NIX2*ENSMUSG0000003645921
Ablim2 / Q8BL65 / actin-binding LIM protein 2 / Q6H8Q1* / actin binding LIM protein family member 2*ENSMUSG0000002909516
Ablim3 / Q69ZX8 / actin binding LIM protein family, member 3 / O94929*ENSMUSG0000003273514
Ablim1 / Q8K4G5 / actin-binding LIM protein 1 / O14639*ENSMUSG0000002508514
Dmtn / Q9WV69 / Dematin / Q08495* / dematin actin binding protein*ENSMUSG000000220994


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IMP
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0043149 stress fiber assembly IEA
 biological_processGO:0050727 regulation of inflammatory response IEA
 biological_processGO:0071346 cellular response to interferon-gamma IDA
 cellular_componentGO:0001725 stress fiber IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045335 phagocytic vesicle IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000358 abnormal cell content/ morphology "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Disc1tm1Kara/Disc1+
Genetic Background: B6.129S6-Disc1tm1Kara

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd28tm1Mak/Cd28tm1Mak,Tnfsf9tm1Thw/Tnfsf9tm1Thw
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6

 MP:0003566 abnormal cell adhesion "altered ability of a cell to adhere to another cell or to a non-cellular component of the environment" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Disc1tm1Kara/Disc1+
Genetic Background: B6.129S6-Disc1tm1Kara

 MP:0011707 impaired fibroblast cell migration "failure of cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium" [MGI:csmith]
Show

Allelic Composition: Disc1tm1Kara/Disc1+
Genetic Background: B6.129S6-Disc1tm1Kara

 MP:0011709 increased fibroblast cell migration "greater frequency of or more rapid cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium" [MGI:csmith]
Show

Allelic Composition: Disc1tm1Kara/Disc1+
Genetic Background: B6.129S6-Disc1tm1Kara

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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