MP:0000063 | reduced bone density | "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315] |
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Allelic Composition: Fermt2tm1.1Gxo/Fermt2tm1.1Gxo,Tg(Col2a1-cre)1Bhr/0 Genetic Background: B6.Cg-Fermt2tm1.1Gxo Tg(Col2a1-cre)1Bhr
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MP:0000075 | absent neurocranium | "missing bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0000149 | abnormal scapula morphology | "malformation of either or both of the large, flat bones of the back part of the shoulder" [J:13049] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0000157 | abnormal sternum morphology | "malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0000160 | kyphosis | "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Whrnhb/Whrnhb Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J
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MP:0000165 | abnormal hypertrophic chondrocyte zone | "anomaly of the cartilage cell matrix layer " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58795] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0000166 | abnormal chondrocyte morphology | "anomalous structure, organization, or differentiation of nondividing cartilage cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0000167 | reduced chondrocyte numbers | "fewer than normal numbers of nondividing cartilage cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61509] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0000547 | short limbs | "reduced average length of the extremities" [MGI:CLS, J:61509] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
Allelic Composition: Fermt2tm1.1Gxo/Fermt2tm1.1Gxo,Tg(Col2a1-cre)1Bhr/0 Genetic Background: B6.Cg-Fermt2tm1.1Gxo Tg(Col2a1-cre)1Bhr
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Whrnhb/Whrnhb Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J
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MP:0001674 | abnormal triploblastic development | "abnormal development of the three primary germ layers" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator] |
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Allelic Composition: Prkg1tm2.1Naw/Prkg1tm2.1Naw Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Fermt2tm1.1Gxo/Fermt2tm1.1Gxo,Tg(Col2a1-cre)1Bhr/0 Genetic Background: B6.Cg-Fermt2tm1.1Gxo Tg(Col2a1-cre)1Bhr
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MP:0001954 | respiratory distress | "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
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Allelic Composition: Fermt2tm1.1Gxo/Fermt2tm1.1Gxo,Tg(Col2a1-cre)1Bhr/0 Genetic Background: B6.Cg-Fermt2tm1.1Gxo Tg(Col2a1-cre)1Bhr
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MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Whrnhb/Whrnhb Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J
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MP:0002543 | brachyphalangia | "abnormally short phalanges" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0002544 | brachydactyly | "abnormally short digits" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0002657 | chondrodystrophy | "abnormal development of the cartilage primordia of long bones, resulting in abnormally short extremities but normal head and trunk" [il:Ira Lu , Mouse Genome Informatics Curator] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0002764 | short tibia | " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0003055 | abnormal epiphyseal plate morphology | "malformed or absent cartilagenous center of ossification on the long bones permitting growth of the bone in both directions during development" [MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: Fermt2tm1.1Gxo/Fermt2tm1.1Gxo,Tg(Col2a1-cre)1Bhr/0 Genetic Background: B6.Cg-Fermt2tm1.1Gxo Tg(Col2a1-cre)1Bhr
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MP:0003109 | short femur | "reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0003419 | delayed endochondral bone ossification | "late onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
Allelic Composition: Fermt2tm1.1Gxo/Fermt2tm1.1Gxo,Tg(Col2a1-cre)1Bhr/0 Genetic Background: B6.Cg-Fermt2tm1.1Gxo Tg(Col2a1-cre)1Bhr
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MP:0003566 | abnormal cell adhesion | "altered ability of a cell to adhere to another cell or to a non-cellular component of the environment" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Prkg1tm2.1Naw/Prkg1tm2.1Naw Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0003662 | abnormal proliferative zone | "germinal layer of the epiphyseal plate where cells are actively dividing as well as producing extracellular matrix" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96254] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0003886 | abnormal embryonic epiblast morphology | "anomaly in the development/organization of the tissue that gives rise to the ectoderm, endoderm and mesoderm of the embryo proper" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Prkg1tm2.1Naw/Prkg1tm2.1Naw Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0004321 | short sternum | "reduced length of the long flat bone of the chest which articulates with clavicle and first seven rib pairs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0004337 | clavicle hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of one or both of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0004338 | small clavicle | "reduced size of one or both of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0004340 | short scapula | "reduced length of either or both of the large, flat bones of the back part of the shoulder" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0004351 | short humerus | "reduced length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0004355 | short radius | "reduced length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0004359 | short ulna | "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0004610 | small vertebrae | "reduced size of the bony segments of the spinal column" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fermt2tm1.1Gxo/Fermt2tm1.1Gxo,Tg(Col2a1-cre)1Bhr/0 Genetic Background: B6.Cg-Fermt2tm1.1Gxo Tg(Col2a1-cre)1Bhr
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MP:0004626 | vertebral compression | "appearance of vertebrae that are flattened laterally along the whole length such that they appear pressed together and take up less rostrocaudal space " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fermt2tm1.1Gxo/Fermt2tm1.1Gxo,Tg(Col2a1-cre)1Bhr/0 Genetic Background: B6.Cg-Fermt2tm1.1Gxo Tg(Col2a1-cre)1Bhr
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MP:0004686 | decreased length of long bones | "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
Allelic Composition: Fermt2tm1.1Gxo/Fermt2tm1.1Gxo,Tg(Col2a1-cre)1Bhr/0 Genetic Background: B6.Cg-Fermt2tm1.1Gxo Tg(Col2a1-cre)1Bhr
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MP:0005508 | abnormal skeleton morphology | "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
Allelic Composition: Fermt2tm1.1Gxo/Fermt2tm1.1Gxo,Tg(Col2a1-cre)1Bhr/0 Genetic Background: B6.Cg-Fermt2tm1.1Gxo Tg(Col2a1-cre)1Bhr
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MP:0006279 | abnormal limb development | "anomaly in the formation of the limbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0006397 | disorganized long bone epiphyseal plate | "a lack of the regular arrangement of the cells or zones of the epiphyseal plate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0008273 | abnormal intramembranous bone ossification | "anomaly in the process of the formation of bone in which osteoblasts secrete a collage-proteoglycan matrix that binds calcium salts and becomes calcified; intramembranous ossification is the way flat bones are formed" [GO:0001957] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0008817 | hematoma | "an abnormal localized accumulation of clotted or partially clotted blood in an organ or a soft tissue space as a result of localized hemorrhage" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0010082 | sternebra fusion | "appearance of one or more sternebrae as a single structure" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0010103 | small thoracic cage | "reduced size of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fermt2tm1.1Gxo/Fermt2tm1.1Gxo,Tg(Col2a1-cre)1Bhr/0 Genetic Background: B6.Cg-Fermt2tm1.1Gxo Tg(Col2a1-cre)1Bhr
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MP:0010879 | decreased trabecular bone volume | "decrease in the amount of space occupied by trabecular bone tissue in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fermt2tm1.1Gxo/Fermt2tm1.1Gxo,Tg(Col2a1-cre)1Bhr/0 Genetic Background: B6.Cg-Fermt2tm1.1Gxo Tg(Col2a1-cre)1Bhr
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MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0011096 | complete embryonic lethality before somite formation | "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith] |
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Allelic Composition: Prkg1tm2.1Naw/Prkg1tm2.1Naw Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Fermt2Gt(AM0293)Wtsi/Fermt2Gt(AM0293)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0012279 | wide sternum | "an increase in the width of the long flat bone of the chest that articulates with the clavicle and first seven rib pairs" [MGI:anna] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0013624 | decreased femur compact bone thickness | "reduced width of the superficial layer of compact bone at the midpoint of the femur" [MGI:csmith] |
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Allelic Composition: Fermt2tm1.1Gxo/Fermt2tm1.1Gxo,Tg(Col2a1-cre)1Bhr/0 Genetic Background: B6.Cg-Fermt2tm1.1Gxo Tg(Col2a1-cre)1Bhr
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MP:0014101 | decreased chondrocyte proliferation | "decreased amount of multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population" [GO:0035988] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0014103 | increased chondrocyte apoptosis | "increased number of chondrocytes undergoing programmed cell death" [MGI:csmith] |
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Allelic Composition: Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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