ENSDARG00000020746


Danio rerio

Features
Gene ID: ENSDARG00000020746
  
Biological name :gfi1aa
  
Synonyms : gfi1aa / growth factor independent 1A transcription repressor a
  
Possible biological names infered from orthology : GFI1 / growth factor independent 1 transcriptional repressor / Q99684
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 10766744
Gene end: 10785866
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000017502
Ensembl peptide - ENSDARP00000147922
NCBI entrez gene - 553814     See in Manteia.
RefSeq - NM_001020776
RefSeq Peptide - NP_001018612
swissprot - F1RBA7
ZFIN ID - ZDB-GENE-050522-534
Ensembl - ENSDARG00000020746
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GFI1ENSGALG00000043650Gallus gallus
 GFI1ENSG00000162676Homo sapiens
 Gfi1ENSMUSG00000029275Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gfi1ab / growth factor independent 1A transcription repressor b / GFI1* / Q99684* / growth factor independent 1 transcriptional repressor*ENSDARG0000004445766
gfi1b / growth factor independent 1B transcription repressor / O70237* / Q5VTD9* / Zinc finger protein Gfi-1b * / growth factor independent 1B transcriptional repressor*ENSDARG0000007994747
fezf2 / Q804Q5 / FEZ family zinc finger 2 / Q9ESP5* / Q8TBJ5* / Fez family zinc finger protein 2 *ENSDARG0000007067724
fezf1 / Q25C93 / FEZ family zinc finger 1 / Q0VDQ9* / A0PJY2* / Fez family zinc finger protein 1 *ENSDARG0000001027024


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR029840  Zinc finger protein Gfi-1/1b


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0030218 erythrocyte differentiation IMP
 biological_processGO:0051569 regulation of histone H3-K4 methylation IEA
 biological_processGO:0060215 primitive hemopoiesis IMP
 molecular_functionGO:0003676 nucleic acid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
Show

 ZFA:0000217 inner ear inner ear increased amount , abnormal
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 ZFA:0000669 head kidney head kidney decreased amount , abnormal
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 ZFA:0005028 ventral wall of dorsal aorta ventral wall of dorsal aorta increased amount , abnormal
ventral wall of dorsal aorta decreased amount , abnormal
ventral wall of dorsal aorta amount , ameliorated
ventral wall of dorsal aorta hematopoietic cell absent , abnormal
ventral wall of dorsal aorta endothelial cell absent , abnormal
Show

 ZFA:0005040 posterior lateral mesoderm posterior lateral mesoderm erythroid lineage cell absent , abnormal
Show

 ZFA:0005237 erythroblast erythroblast decreased amount , abnormal
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 ZFA:0009015 erythroid progenitor cell erythroid progenitor cell decreased amount , abnormal
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 ZFA:0009043 circulating cell circulating cell erythroblast decreased amount , abnormal
Show

 ZFA:0009323 thrombocyte thrombocyte increased amount , abnormal
Show

 ZFA:0009325 erythroid lineage cell erythroid lineage cell hemoglobin complex decreased amount , abnormal
Show

 ZFA:0009354 hematopoietic multipotent progenitor cell hematopoietic multipotent progenitor cell absent , abnormal
hematopoietic multipotent progenitor cell decreased amount , abnormal
Show

 ZFA:0009356 myeloid lineage restricted progenitor cell myeloid lineage restricted progenitor cell increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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