ENSDARG00000021895


Danio rerio

Features
Gene ID: ENSDARG00000021895
  
Biological name :disc1
  
Synonyms : disc1 / disrupted in schizophrenia 1
  
Possible biological names infered from orthology : Disrupted in schizophrenia 1 homolog / Q811T9 / Q9NRI5
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 49057081
Gene end: 49144881
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000035679
Ensembl peptide - ENSDARP00000124789
NCBI entrez gene - 407621     See in Manteia.
RefSeq - NM_001142263
RefSeq Peptide - NP_001135735
swissprot - F1QQ50
ZFIN ID - ZDB-GENE-090122-1
Ensembl - ENSDARG00000021895
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DISC1ENSGALG00000039349Gallus gallus
 DISC1ENSG00000162946Homo sapiens
 Disc1ENSMUSG00000043051Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026081  Disrupted in schizophrenia 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001755 neural crest cell migration IMP
 biological_processGO:0007399 nervous system development IMP
 biological_processGO:0007420 brain development IMP
 biological_processGO:0010001 glial cell differentiation IMP
 biological_processGO:0010470 regulation of gastrulation IMP
 biological_processGO:0021755 eurydendroid cell differentiation IMP
 biological_processGO:0021778 oligodendrocyte cell fate specification IMP
 biological_processGO:0021854 hypothalamus development IMP
 biological_processGO:0033555 multicellular organismal response to stress IMP
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IMP
 biological_processGO:0060027 convergent extension involved in gastrulation IMP
 biological_processGO:0060351 cartilage development involved in endochondral bone morphogenesis IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain morphology , abnormal
Show

 ZFA:0000029 hindbrain hindbrain oligodendrocyte decreased amount , abnormal
hindbrain cellular quality , abnormal
hindbrain neuron disorganized , abnormal
Show

 ZFA:0000032 hypothalamus hypothalamus increased distribution , abnormal
hypothalamus decreased distribution , abnormal
hypothalamus neuron differentiation process quality , abnormal
hypothalamus neuron irregular spatial pattern , abnormal
Show

 ZFA:0000076 swim bladder swim bladder malformed , abnormal
swim bladder uninflated , abnormal
Show

 ZFA:0000100 cerebellum cerebellum eurydendroid cell decreased amount , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye malformed , abnormal
Show

 ZFA:0000109 forebrain forebrain truncated , abnormal
Show

 ZFA:0000110 fourth ventricle fourth ventricle decreased size , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000155 somite somite increased width , abnormal
somite condensed , abnormal
Show

 ZFA:0000159 tectal ventricle tectal ventricle decreased size , abnormal
Show

 ZFA:0000161 third ventricle third ventricle absent , abnormal
Show

 ZFA:0000170 basibranchial basibranchial aplastic , abnormal
Show

 ZFA:0000231 lateral recess lateral recess decreased distribution , abnormal
Show

 ZFA:0000295 trigeminal ganglion trigeminal ganglion glial cell increased amount , abnormal
Show

 ZFA:0000338 diencephalic white matter diencephalic white matter lacks parts or has fewer parts of type postoptic commissure , abnormal
Show

 ZFA:0000470 preoptic area preoptic area decreased distribution , abnormal
preoptic area increased distribution , abnormal
Show

 ZFA:0000597 telencephalic white matter telencephalic white matter lacks parts or has fewer parts of type anterior commissure , abnormal
Show

 ZFA:0000634 caudal hypothalamic zone caudal hypothalamic zone decreased distribution , abnormal
caudal hypothalamic zone increased distribution , abnormal
Show

 ZFA:0001056 myotome myotome U-shaped , abnormal
Show

 ZFA:0001094 whole organism whole organism lacks parts or has fewer parts of type facial nerve motor nucleus , abnormal
whole organism lacks parts or has fewer parts of type trigeminal motor nucleus , abnormal
whole organism lacks parts or has fewer parts of type motor nucleus of vagal nerve , abnormal
whole organism lacks parts or has fewer parts of type cranial nerve X , abnormal
whole organism lacks parts or has fewer parts of type cranial nerve VII , abnormal
whole organism lacks parts or has fewer parts of type cranial nerve V , abnormal
whole organism decreased length , abnormal
whole organism decreased amount , abnormal
Show

 ZFA:0001115 trunk trunk curved , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved dorsal , abnormal
post-vent region bent , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin malformed , abnormal
Show

 ZFA:0001194 cranial neural crest cranial neural crest increased size , abnormal
Show

 ZFA:0001204 axial mesoderm axial mesoderm increased width , abnormal
axial mesoderm sigmoid , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased size , abnormal
Meckels cartilage malformed , abnormal
Show

 ZFA:0001259 forebrain ventricle forebrain ventricle decreased size , abnormal
Show

 ZFA:0001261 ventricular system ventricular system morphology , abnormal
Show

 ZFA:0001314 posterior lateral line ganglion posterior lateral line ganglion glial cell increased amount , abnormal
Show

 ZFA:0001321 neurocranial trabecula neurocranial trabecula decreased size , abnormal
Show

 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage malformed , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage decreased size , abnormal
ceratohyal cartilage malformed , abnormal
Show

 ZFA:0001405 ethmoid cartilage ethmoid cartilage decreased size , abnormal
Show

 ZFA:0001458 cranial cartilage cranial cartilage malformed , abnormal
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 ZFA:0001510 basihyal cartilage basihyal cartilage aplastic , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage aplastic , abnormal
ceratobranchial cartilage absent , abnormal
Show

 ZFA:0001682 white matter white matter lacks parts or has fewer parts of type supraoptic tract , abnormal
Show

 ZFA:0005145 muscle muscle disorganized , abnormal
Show

 ZFA:0005179 MiP motor neuron MiP motor neuron decreased amount , abnormal
Show

 ZFA:0007067 vagal ganglion vagal ganglion malformed , abnormal
Show

 ZFA:0009244 primary motor neuron primary motor neuron increased branchiness , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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