ENSDARG00000022845


Danio rerio

Features
Gene ID: ENSDARG00000022845
  
Biological name :lias
  
Synonyms : lias / lipoic acid synthetase
  
Possible biological names infered from orthology : Lipoyl synthase, mitochondrial / O43766 / Q99M04
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 23274710
Gene end: 23283468
  
Corresponding Affymetrix probe sets: Dr.16722.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000035286
NCBI entrez gene - 393528     See in Manteia.
RefSeq - NM_001110401
RefSeq Peptide - NP_001103871
swissprot - A0A0R4I9B1
ZFIN ID - ZDB-GENE-040426-1528
Ensembl - ENSDARG00000022845
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000014312Gallus gallus
 ENSGALG00000031933Gallus gallus
 LIASENSG00000121897Homo sapiens
 LiasENSMUSG00000029199Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003698  Lipoyl synthase
 IPR006638  Elp3/MiaB/NifB
 IPR007197  Radical SAM
 IPR013785  Aldolase-type TIM barrel
 IPR031691  Lipoyl synthase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009107 lipoate biosynthetic process IEA
 biological_processGO:0009249 protein lipoylation IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016783 sulfurtransferase activity IEA
 molecular_functionGO:0016992 lipoate synthase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000105187 gcshb / glycine cleavage system protein H (aminomethyl carrier), b / GCSH* / P23434* / Q91WK5* / AC092718.3* / AC092718.8* / glycine cleavage system protein H* / Glycine cleavage system H p...  / reaction






 

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contact: otassy@igbmc.fr