ENSDARG00000025220


Danio rerio

Features
Gene ID: ENSDARG00000025220
  
Biological name :sppl3
  
Synonyms : signal peptide peptidase 3 / sppl3
  
Possible biological names infered from orthology : Q8TCT6 / Q9CUS9 / signal peptide peptidase like 3
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 17235370
Gene end: 17433878
  
Corresponding Affymetrix probe sets: Dr.5584.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000028735
Ensembl peptide - ENSDARP00000109436
NCBI entrez gene - 548609     See in Manteia.
swissprot - F1RDS1
swissprot - Q5BP97
ZFIN ID - ZDB-GENE-050913-71
Ensembl - ENSDARG00000025220
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPPL3ENSGALG00000006979Gallus gallus
 SPPL3ENSG00000157837Homo sapiens
 Sppl3ENSMUSG00000029550Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sppl2 / signal peptide peptidase-like 2 / Q8TCT7* / Q3TD49* / SPPL2B* / signal peptide peptidase like 2B*ENSDARG0000003044825
hm13 / histocompatibility (minor) 13 / H13* / Q8TCT9* / Q9D8V0* / Minor histocompatibility antigen H13 *ENSDARG0000003784624


Protein motifs (from Interpro)
Interpro ID Name
 IPR006639  Presenilin/signal peptide peptidase
 IPR007369  Peptidase A22B, signal peptide peptidase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0043523 regulation of neuron apoptotic process IMP
 cellular_componentGO:0005765 lysosomal membrane IBA
 cellular_componentGO:0005791 rough endoplasmic reticulum ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030660 Golgi-associated vesicle membrane IBA
 cellular_componentGO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane IBA
 cellular_componentGO:0071556 integral component of lumenal side of endoplasmic reticulum membrane IBA
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IEA
 molecular_functionGO:0042500 aspartic endopeptidase activity, intramembrane cleaving ISS
 molecular_functionGO:0042803 protein homodimerization activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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