ENSDARG00000025504


Danio rerio

Features
Gene ID: ENSDARG00000025504
  
Biological name :gucy2f
  
Synonyms : guanylate cyclase 2F, retinal / gucy2f
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 29362714
Gene end: 29381134
  
Corresponding Affymetrix probe sets: Dr.11183.1.A1_at (Zebrafish Array)   Dr.12591.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000090689
Ensembl peptide - ENSDARP00000109090
NCBI entrez gene - 140424     See in Manteia.
swissprot - B3DHF2
swissprot - F1QWF7
ZFIN ID - ZDB-GENE-011128-7
Ensembl - ENSDARG00000025504
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000000808Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gc2 / guanylyl cyclase 2 / GUCY2F* / P51841* / Q5SDA5* / Retinal guanylyl cyclase 2 * / guanylate cyclase 2F, retinal*ENSDARG0000001832958
gucy2d / guanylate cyclase 2D, retinal / Gucy2e* / P52785* / Q02846* / Guanylyl cyclase GC-E *ENSDARG0000002682054
npr1b / natriuretic peptide receptor 1b / NPR1* / P16066* / P18293* / natriuretic peptide receptor 1*ENSDARG0000001875030
npr1a / natriuretic peptide receptor 1a / NPR1* / P16066* / P18293* / natriuretic peptide receptor 1*ENSDARG0000003175130
npr2 / natriuretic peptide receptor 2 / P20594*ENSDARG0000010439330
gucy2g / guanylate cyclase 2g / Q6TL19*ENSDARG0000007677629
si:ch73-139e5.4 / GUCY2C* / P25092* / Q3UWA6* / guanylate cyclase 2C* / Heat-stable enterotoxin receptor *ENSDARG0000005604528
si:dkey-37g12.1ENSDARG0000006026428
gucy2c / guanylate cyclase 2C / P25092*ENSDARG0000001432027
gucy1b2 / guanylate cyclase 1, soluble, beta 2ENSDARG0000005659116
gucy1b1 / guanylate cyclase 1 soluble subunit beta 1 / O54865* / Q02153* / guanylate cyclase 1, soluble, beta 1*ENSDARG0000008679014
gucy1a1 / guanylate cyclase 1 soluble subunit alpha 1 / Q02108* / Q9ERL9* / guanylate cyclase 1, soluble, alpha 1*ENSDARG0000001378714
GUCY1A2 / guanylate cyclase 1 soluble subunit alpha 2 / P33402*ENSDARG0000009318513
si:ch211-215j19.12ENSDARG0000010407210
si:dkey-239n17.6ENSDARG000000958482


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001054  Adenylyl cyclase class-3/4/guanylyl cyclase
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001828  Receptor, ligand binding region
 IPR011009  Protein kinase-like domain superfamily
 IPR018297  Adenylyl cyclase class-4/guanylyl cyclase, conserved site
 IPR028082  Periplasmic binding protein-like I
 IPR029787  Nucleotide cyclase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006182 cGMP biosynthetic process IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007601 visual perception IMP
 biological_processGO:0009190 cyclic nucleotide biosynthetic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0035845 photoreceptor cell outer segment organization IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0008074 guanylate cyclase complex, soluble IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004383 guanylate cyclase activity IMP
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016849 phosphorus-oxygen lyase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000152 retina retina dystrophic , abnormal
Show

 ZFA:0001466 photoreceptor outer segment layer photoreceptor outer segment layer shortened , abnormal
Show

 ZFA:0009262 retinal cone cell retinal cone cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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