ENSDARG00000026820


Danio rerio

Features
Gene ID: ENSDARG00000026820
  
Biological name :gucy2d
  
Synonyms : guanylate cyclase 2D, retinal / gucy2d
  
Possible biological names infered from orthology : Guanylyl cyclase GC-E / Gucy2e / P52785 / Q02846
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 38123633
Gene end: 38161033
  
Corresponding Affymetrix probe sets: Dr.20996.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000088541
Ensembl peptide - ENSDARP00000113061
NCBI entrez gene - 140426     See in Manteia.
RefSeq - NM_131866
RefSeq Peptide - NP_571941
swissprot - F1QSL9
swissprot - A2BFQ0
ZFIN ID - ZDB-GENE-011128-9
Ensembl - ENSDARG00000026820
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GUCY2DENSG00000132518Homo sapiens
 Gucy2eENSMUSG00000020890Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gucy2f / guanylate cyclase 2F, retinalENSDARG0000002550451
gc2 / guanylyl cyclase 2 / GUCY2F* / P51841* / Q5SDA5* / Retinal guanylyl cyclase 2 * / guanylate cyclase 2F, retinal*ENSDARG0000001832949
gucy2g / guanylate cyclase 2g / Q6TL19*ENSDARG0000007677628
npr1a / natriuretic peptide receptor 1a / NPR1* / P16066* / P18293* / natriuretic peptide receptor 1*ENSDARG0000003175127
npr1b / natriuretic peptide receptor 1b / NPR1* / P16066* / P18293* / natriuretic peptide receptor 1*ENSDARG0000001875027
npr2 / natriuretic peptide receptor 2 / P20594*ENSDARG0000010439327
si:dkey-37g12.1ENSDARG0000006026425
gucy2c / guanylate cyclase 2C / P25092*ENSDARG0000001432025
si:ch73-139e5.4 / GUCY2C* / P25092* / Q3UWA6* / guanylate cyclase 2C* / Heat-stable enterotoxin receptor *ENSDARG0000005604525
gucy1b2 / guanylate cyclase 1, soluble, beta 2ENSDARG0000005659115
gucy1a1 / guanylate cyclase 1 soluble subunit alpha 1 / Q02108* / Q9ERL9* / guanylate cyclase 1, soluble, alpha 1*ENSDARG0000001378713
GUCY1A2 / guanylate cyclase 1 soluble subunit alpha 2 / P33402*ENSDARG0000009318512
gucy1b1 / guanylate cyclase 1 soluble subunit beta 1 / O54865* / Q02153* / guanylate cyclase 1, soluble, beta 1*ENSDARG0000008679011
si:ch211-215j19.12ENSDARG000001040729
si:dkey-239n17.6ENSDARG000000958482


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001054  Adenylyl cyclase class-3/4/guanylyl cyclase
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001828  Receptor, ligand binding region
 IPR011009  Protein kinase-like domain superfamily
 IPR011645  Haem NO binding associated
 IPR018297  Adenylyl cyclase class-4/guanylyl cyclase, conserved site
 IPR028082  Periplasmic binding protein-like I
 IPR029787  Nucleotide cyclase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006182 cGMP biosynthetic process IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0009190 cyclic nucleotide biosynthetic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0008074 guanylate cyclase complex, soluble IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004383 guanylate cyclase activity IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016849 phosphorus-oxygen lyase activity IEA


Pathways (from Reactome)
Pathway description
Inactivation, recovery and regulation of the phototransduction cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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