ENSDARG00000026048


Danio rerio

Features
Gene ID: ENSDARG00000026048
  
Biological name :tsc1a
  
Synonyms : tsc1a / TSC complex subunit 1a
  
Possible biological names infered from orthology : Hamartin / Q92574 / Q9EP53 / TSC1 / TSC complex subunit 1
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 29652198
Gene end: 29672144
  
Corresponding Affymetrix probe sets: Dr.15438.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000153412
Ensembl peptide - ENSDARP00000035073
NCBI entrez gene - 337167     See in Manteia.
RefSeq - NM_200052
RefSeq Peptide - NP_956346
swissprot - A2BFC8
ZFIN ID - ZDB-GENE-030131-9111
Ensembl - ENSDARG00000026048
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000043548Gallus gallus
 ENSGALG00000003500Gallus gallus
 TSC1ENSG00000165699Homo sapiens
 Tsc1ENSMUSG00000026812Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tsc1b / TSC complex subunit 1b / TSC1* / Q9EP53* / Q92574* / Hamartin * / TSC complex subunit 1*ENSDARG0000005791851


Protein motifs (from Interpro)
Interpro ID Name
 IPR007483  Hamartin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007368 determination of left/right symmetry IMP
 biological_processGO:0032006 regulation of TOR signaling IMP
 biological_processGO:0032007 negative regulation of TOR signaling IBA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IBA
 biological_processGO:0043087 regulation of GTPase activity IBA
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway IBA
 biological_processGO:0048793 pronephros development IMP
 biological_processGO:0051726 regulation of cell cycle IBA
 biological_processGO:0060271 cilium assembly IMP
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0033596 TSC1-TSC2 complex IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000051 otic vesicle otic vesicle cilium increased length , abnormal
Show

 ZFA:0000121 lateral plate mesoderm lateral plate mesoderm bilateral symmetry , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct cilium increased length , abnormal
pronephric duct increased diameter , abnormal
Show

 ZFA:0000151 pronephros pronephros cystic , abnormal
Show

 ZFA:0000360 heart tube heart tube bilateral symmetry , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
Show

 ZFA:0001557 pronephric glomerulus pronephric glomerulus cystic , abnormal
Show

 ZFA:0001558 pronephric tubule pronephric tubule cystic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr