ENSDARG00000030364


Danio rerio

Features
Gene ID: ENSDARG00000030364
  
Biological name :angpt1
  
Synonyms : angiopoietin 1 / angpt1
  
Possible biological names infered from orthology : O08538 / Q15389
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 46812272
Gene end: 46957968
  
Corresponding Affymetrix probe sets: Dr.12619.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000043712
swissprot - Q1MT43
ZFIN ID - ZDB-GENE-010817-1
Ensembl - ENSDARG00000030364
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ANGPT1ENSGALG00000029983Gallus gallus
 ANGPT1ENSG00000154188Homo sapiens
 Angpt1ENSMUSG00000022309Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
angpt4 / angiopoietin 4 / Q9Y264*ENSDARG0000007678753
angpt2a / angiopoietin 2a / ANGPT2* / O15123* / O35608* / angiopoietin 2*ENSDARG0000001494649
angpt2b / angiopoietin 2bENSDARG0000005390647
angptl1a / angiopoietin-like 1a / Q640P2* / O95841* / ANGPTL1* / angiopoietin like 1* / Angiopoietin-related protein 1 *ENSDARG0000001207125
angptl6 / angiopoietin-like 6 / Q8NI99*ENSDARG0000002026525
angptl2b / angiopoietin-like 2bENSDARG0000006836924
fgl2b / fibrinogen-like 2b / FGL2* / P12804* / Q14314* / Fibroleukin * / fibrinogen like 2*ENSDARG0000001968624
angptl2a / angiopoietin-like 2aENSDARG0000002403024
angptl1b / angiopoietin-like 1b / O95841* / ANGPTL1* / angiopoietin like 1*ENSDARG0000010015924
si:ch211-203k16.3ENSDARG0000006930523
fibcd1 / fibrinogen C domain containing 1 / A2AV25* / Q8N539* / Fibrinogen C domain-containing protein 1 *ENSDARG0000006039322
angptl7 / angiopoietin-like 7 / O43827* / Q8R1Q3* / Angiopoietin-related protein 7 *ENSDARG0000002758222
fgl2a / fibrinogen-like 2a / FGL2* / P12804* / Q14314* / Fibroleukin * / fibrinogen like 2*ENSDARG0000001986122
si:ch211-157b11.8ENSDARG0000006041320
wu:fj11g02 / si:zfos-2330d3.1 / MFAP4 (1 of many) / MFAP4* / P55083* / Q9D1H9* / microfibril associated protein 4* / Microfibril-associated glycoprotein 4 *ENSDARG0000003868118
si:zfos-2330d3.1 / MFAP4 (1 of many) / si:ch1073-110a20.2 / MFAP4* / P55083* / Q9D1H9* / microfibril associated protein 4* / Microfibril-associated glycoprotein 4 *ENSDARG0000003868318
MFAP4 (1 of many) / si:ch1073-110a20.7 / MFAP4* / P55083* / Q9D1H9* / microfibril associated protein 4* / Microfibril-associated glycoprotein 4 *ENSDARG0000009055717
mfap4 / microfibril associated protein 4 / P55083* / Q9D1H9* / Microfibril-associated glycoprotein 4 *ENSDARG0000009078317
si:ch1073-110a20.3 / MFAP4* / Q9D1H9* / P55083* / microfibril associated protein 4* / Microfibril-associated glycoprotein 4 *ENSDARG0000009658617
zgc:173915 / si:zfos-2330d3.3 / MFAP4 (1 of many) / MFAP4* / P55083* / Q9D1H9* / microfibril associated protein 4* / Microfibril-associated glycoprotein 4 *ENSDARG0000008966717


Protein motifs (from Interpro)
Interpro ID Name
 IPR002181  Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
 IPR014715  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2
 IPR014716  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
 IPR020837  Fibrinogen, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001568 blood vessel development IGI
 biological_processGO:0007420 brain development IMP
 biological_processGO:0048014 Tie signaling pathway IEA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IEA


Pathways (from Reactome)
Pathway description
Tie2 Signaling
RAF/MAP kinase cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased size , abnormal
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 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000186 common cardinal vein common cardinal vein morphology , abnormal
Show

 ZFA:0005035 subintestinal vein subintestinal vein morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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