ENSDARG00000030530


Danio rerio

Features
Gene ID: ENSDARG00000030530
  
Biological name :slc22a2
  
Synonyms : slc22a2 / solute carrier family 22 (organic cation transporter), member 2
  
Possible biological names infered from orthology : O08966 / O15244 / O15245 / O70577 / SLC22A1 / solute carrier family 22 member 1 / solute carrier family 22 member 2
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 42668875
Gene end: 42688487
  
Corresponding Affymetrix probe sets: Dr.13231.2.S1_a_at (Zebrafish Array)   Dr.5676.1.A1_at (Zebrafish Array)   NM_213150_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000048889
NCBI entrez gene - 406424     See in Manteia.
RefSeq - NM_213150
RefSeq Peptide - NP_998315
swissprot - Q5VSI5
ZFIN ID - ZDB-GENE-040426-2167
Ensembl - ENSDARG00000030530
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000011579Gallus gallus
 ENSGALG00000011615Gallus gallus
 O15244ENSG00000112499Homo sapiens
 O15245ENSG00000175003Homo sapiens
 O08966ENSMUSG00000023829Mus musculus
 O70577ENSMUSG00000040966Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
oct2 / organic cation transporter 2 / O75751* / SLC22A3* / solute carrier family 22 member 3*ENSDARG0000005877545
slc22a13b / solute carrier family 22 member 13b / Q9Y267* / Q9Y226* / SLC22A14* / SLC22A13* / solute carrier family 22 member 13* / solute carrier family 22 member 14*ENSDARG0000005916630
slc22a4 / solute carrier family 22 (organic cation/zwitterion transporter), member 4 / Q9WTN6* / Q9Z0E8* / Q9Z306* / O76082* / Q9H015* / SLC22A5* / Slc22a21* / solute carrier family 22 memb...ENSDARG0000000533529
slc22a7a / solute carrier family 22 (organic anion transporter), member 7a / Q9Y694* / SLC22A7* / solute carrier family 22 member 7*ENSDARG0000005602829
slc22a21 / solute carrier family 22 (organic cation transporter), member 21 / Q9WTN6* / Q9Z0E8* / Q9Z306* / O76082* / Q9H015* / SLC22A4* / SLC22A5* / solute carrier family 22 member 5* / so...ENSDARG0000009411229
oatx / organic anion transporter X / Q8IVM8* / Q4U2R8* / Q8TCC7* / Q96S37* / Q9NSA0* / Q8N4F4* / Q63ZE4* / Q6T423* / SLC22A9* / SLC22A8* / SLC22A6* / SLC22A12* / SLC22A10* / SLC22A11* / SLC...ENSDARG0000001971328
si:dkey-166k12.1ENSDARG0000005469028
slc22a6l / solute carrier family 22 (organic anion transporter), member 6, like / Q8N4F4* / Q8R0S9* / Q8TCC7* / Q8VC69* / Q63ZE4* / Q76M72* / Q8IVM8* / O88909* / Q4U2R8* / Q6T423* / Q8VCA0*...ENSDARG0000005552328
slc22a15 / solute carrier family 22, member 15 / Q504N2* / Q8IZD6*ENSDARG0000005544527
slc22a7b.1 / solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 1ENSDARG0000005664327
slc22a5 / solute carrier family 22 (organic cation/carnitine transporter), member 5 / Q9H015* / O76082* / SLC22A4* / solute carrier family 22 member 4* / solute carrier family 22 member 5*ENSDARG0000010102127
slc22a7b.3 / solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 3ENSDARG0000006218226
slc22a16 / solute carrier family 22 (organic cation/carnitine transporter), member 16 / Q86VW1* / Q497L8* / solute carrier family 22 member 16* / solute carrier family 22 (organic cation tr...ENSDARG0000001586926
zmp:0000001102ENSDARG0000005665226
slc22a7b.2 / solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 2ENSDARG0000009125223
slc22a13a / solute carrier family 22 member 13aENSDARG0000005655122
si:dkey-119m7.4ENSDARG0000007104922


Protein motifs (from Interpro)
Interpro ID Name
 IPR004749  Organic cation transport protein/SVOP
 IPR005828  Major facilitator, sugar transporter-like
 IPR005829  Sugar transporter, conserved site
 IPR020846  Major facilitator superfamily domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015697 quaternary ammonium group transport IEA
 biological_processGO:0015711 organic anion transport IEA
 biological_processGO:0015872 dopamine transport IBA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0005329 dopamine transmembrane transporter activity IBA
 molecular_functionGO:0008514 organic anion transmembrane transporter activity IBA
 molecular_functionGO:0015651 quaternary ammonium group transmembrane transporter activity IBA
 molecular_functionGO:0022857 transmembrane transporter activity IDA


Pathways (from Reactome)
Pathway description
Neurotransmitter clearance
Norepinephrine Neurotransmitter Release Cycle
Abacavir transmembrane transport
Na+/Cl- dependent neurotransmitter transporters
Organic cation transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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