ENSDARG00000005335


Danio rerio

Features
Gene ID: ENSDARG00000005335
  
Biological name :slc22a4
  
Synonyms : slc22a4 / solute carrier family 22 (organic cation/zwitterion transporter), member 4
  
Possible biological names infered from orthology : O76082 / Q9H015 / Q9WTN6 / Q9Z0E8 / Q9Z306 / Slc22a21 / SLC22A5 / solute carrier family 22 member 4 / solute carrier family 22 member 5 / solute carrier family 22 (organic cation transporter), member 21 / solute carrier family 22 (organic cation transporter), member 5
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 45897814
Gene end: 45903536
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000021163
NCBI entrez gene - 393822     See in Manteia.
RefSeq - NM_200849
RefSeq Peptide - NP_957143
swissprot - F1QKX0
ZFIN ID - ZDB-GENE-040426-1517
Ensembl - ENSDARG00000005335
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC22A4ENSGALG00000035026Gallus gallus
 SLC22A5ENSGALG00000036920Gallus gallus
 O76082ENSG00000197375Homo sapiens
 Q9H015ENSG00000197208Homo sapiens
 Q9WTN6ENSMUSG00000063652Mus musculus
 Q9Z0E8ENSMUSG00000018900Mus musculus
 Q9Z306ENSMUSG00000020334Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
slc22a21 / solute carrier family 22 (organic cation transporter), member 21 / Q9WTN6* / Q9Z0E8* / Q9Z306* / O76082* / Q9H015* / SLC22A4* / SLC22A5* / solute carrier family 22 member 5* / so...ENSDARG0000009411251
slc22a5 / solute carrier family 22 (organic cation/carnitine transporter), member 5 / Q9H015* / O76082* / SLC22A4* / solute carrier family 22 member 4* / solute carrier family 22 member 5*ENSDARG0000010102147
slc22a2 / solute carrier family 22 (organic cation transporter), member 2 / O15244* / O70577* / O15245* / O08966* / SLC22A1* / solute carrier family 22 member 1* / solute carrier family 22 member 2*ENSDARG0000003053030
si:dkey-166k12.1ENSDARG0000005469030
slc22a7a / solute carrier family 22 (organic anion transporter), member 7a / Q9Y694* / SLC22A7* / solute carrier family 22 member 7*ENSDARG0000005602829
oatx / organic anion transporter X / Q8IVM8* / Q4U2R8* / Q8TCC7* / Q96S37* / Q9NSA0* / Q8N4F4* / Q63ZE4* / Q6T423* / SLC22A9* / SLC22A8* / SLC22A6* / SLC22A12* / SLC22A10* / SLC22A11* / SLC...ENSDARG0000001971329
slc22a13b / solute carrier family 22 member 13b / Q9Y267* / Q9Y226* / SLC22A14* / SLC22A13* / solute carrier family 22 member 13* / solute carrier family 22 member 14*ENSDARG0000005916629
slc22a6l / solute carrier family 22 (organic anion transporter), member 6, like / Q8N4F4* / Q8R0S9* / Q8TCC7* / Q8VC69* / Q63ZE4* / Q76M72* / Q8IVM8* / O88909* / Q4U2R8* / Q6T423* / Q8VCA0*...ENSDARG0000005552329
slc22a7b.3 / solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 3ENSDARG0000006218228
slc22a16 / solute carrier family 22 (organic cation/carnitine transporter), member 16 / Q86VW1* / Q497L8* / solute carrier family 22 member 16* / solute carrier family 22 (organic cation tr...ENSDARG0000001586928
zmp:0000001102ENSDARG0000005665228
slc22a7b.1 / solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 1ENSDARG0000005664326
oct2 / organic cation transporter 2 / O75751* / SLC22A3* / solute carrier family 22 member 3*ENSDARG0000005877526
slc22a13a / solute carrier family 22 member 13aENSDARG0000005655126
slc22a7b.2 / solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 2ENSDARG0000009125225
slc22a15 / solute carrier family 22, member 15 / Q504N2* / Q8IZD6*ENSDARG0000005544524
si:dkey-119m7.4ENSDARG0000007104922


Protein motifs (from Interpro)
Interpro ID Name
 IPR005828  Major facilitator, sugar transporter-like
 IPR005829  Sugar transporter, conserved site
 IPR020846  Major facilitator superfamily domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001887 selenium compound metabolic process IDA
 biological_processGO:0015698 inorganic anion transport IMP
 biological_processGO:0015711 organic anion transport IEA
 biological_processGO:0050787 detoxification of mercury ion IDA
 biological_processGO:0051597 response to methylmercury IMP
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0008514 organic anion transmembrane transporter activity IBA
 molecular_functionGO:0022857 transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Import of palmitoyl-CoA into the mitochondrial matrix
Organic cation transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism dead , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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