ENSMUSG00000063652


Mus musculus

Features
Gene ID: ENSMUSG00000063652
  
Biological name :Slc22a21
  
Synonyms : Q9WTN6 / Slc22a21 / solute carrier family 22 (organic cation transporter), member 21
  
Possible biological names infered from orthology : O76082 / SLC22A5 / solute carrier family 22 member 5
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B1.3
Gene start: 53949965
Gene end: 53980332
  
Corresponding Affymetrix probe sets: 10385883 (MoGene1.0st)   1449215_at (Mouse Genome 430 2.0 Array)   1450395_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123180
Ensembl peptide - ENSMUSP00000075814
Ensembl peptide - ENSMUSP00000114966
NCBI entrez gene - 56517     See in Manteia.
MGI - MGI:1929481
RefSeq - XM_011249156
RefSeq - XM_006533805
RefSeq - XM_006533807
RefSeq - XM_006533808
RefSeq - XM_006533809
RefSeq - XM_011249155
RefSeq - NM_019723
RefSeq - XM_006533804
RefSeq Peptide - NP_062697
swissprot - F6YI98
swissprot - D6RDB6
swissprot - A2RSK7
swissprot - Q9WTN6
Ensembl - ENSMUSG00000063652
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc22a21ENSDARG00000094112Danio rerio
 slc22a4ENSDARG00000005335Danio rerio
 slc22a5ENSDARG00000101021Danio rerio
 SLC22A5ENSGALG00000036920Gallus gallus
 O76082ENSG00000197375Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Z0E8 / Slc22a5 / solute carrier family 22 (organic cation transporter), member 5 / O76082* / solute carrier family 22 member 5*ENSMUSG0000001890083
Q9Z306 / Slc22a4 / Solute carrier family 22 member 4 / Q9H015*ENSMUSG0000002033469
O08966 / Slc22a1 / Solute carrier family 22 member 1 / O15245*ENSMUSG0000002382932
O70577 / Slc22a2 / Solute carrier family 22 member 2 / O15244*ENSMUSG0000004096631
Slc22a7 / solute carrier family 22 member 7 / Q9Y694*ENSMUSG0000006714431
Q9WTW5 / Slc22a3 / solute carrier family 22 (organic cation transporter), member 3 / O75751* / solute carrier family 22 member 3*ENSMUSG0000002382830
Q80UJ1 / Slc22a20 / Solute carrier family 22 member 20 ENSMUSG0000003745130
Q8R0S9 / Slc22a22 / Mus musculus solute carrier family 22 (organic cation transporter), member 22 (Slc22a22), transcript variant 2, mRNA.ENSMUSG0000002236629
Q504N2 / Slc22a15 / Solute carrier family 22 member 15 / Q8IZD6*ENSMUSG0000003314728
Q8VC69 / Slc22a6 / Solute carrier family 22 member 6 / Q4U2R8*ENSMUSG0000002465028
Q6A4L0 / Slc22a13 / Solute carrier family 22 member 13 / Q9Y226*ENSMUSG0000007402828
O88909 / Slc22a8 / Solute carrier family 22 member 8 / Q8TCC7*ENSMUSG0000006379628
Slc22a28 / Q8IVM8* / Q6T423* / SLC22A9* / SLC22A25* / solute carrier family 22 member 9* / solute carrier family 22 member 25*ENSMUSG0000006359027
Slc22a12 / solute carrier family 22 member 12 / Q96S37*ENSMUSG0000006174227
Slc22a26 / solute carrier family 22 (organic cation transporter), member 26 / Q8IVM8* / Q6T423* / SLC22A9* / SLC22A25* / solute carrier family 22 member 9* / solute carrier family 22 member 25*ENSMUSG0000005330327
Slc22a30 / solute carrier family 22, member 30 / Q8IVM8* / Q6T423* / SLC22A9* / SLC22A25* / solute carrier family 22 member 9* / solute carrier family 22 member 25*ENSMUSG0000005256227
Q8VCA0 / Slc22a19 / Solute carrier family 22 member 19 / Q8IVM8* / Q6T423* / SLC22A9* / SLC22A25* / solute carrier family 22 member 9* / solute carrier family 22 member 25*ENSMUSG0000002475726
Q497L8 / Slc22a16 / solute carrier family 22 (organic cation transporter), member 16 / Q86VW1* / solute carrier family 22 member 16*ENSMUSG0000001983426
Slc22a29 / solute carrier family 22. member 29 / Q8IVM8* / Q6T423* / SLC22A9* / SLC22A25* / solute carrier family 22 member 9* / solute carrier family 22 member 25*ENSMUSG0000007504426
Q76M72 / Slc22a27 / Solute carrier family 22 member 27 / Q8IVM8* / Q6T423* / SLC22A9* / SLC22A25* / solute carrier family 22 member 9* / solute carrier family 22 member 25*ENSMUSG0000006765626


Protein motifs (from Interpro)
Interpro ID Name
 IPR004749  Organic cation transport protein/SVOP
 IPR005828  Major facilitator, sugar transporter-like
 IPR005829  Sugar transporter, conserved site
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0009437 carnitine metabolic process IBA
 biological_processGO:0015711 organic anion transport IEA
 biological_processGO:0015879 carnitine transport IDA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 biological_processGO:1902603 carnitine transmembrane transport IEA
 cellular_componentGO:0005777 peroxisome IDA
 cellular_componentGO:0005778 peroxisomal membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031231 intrinsic component of peroxisomal membrane IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008514 organic anion transmembrane transporter activity IBA
 molecular_functionGO:0015226 carnitine transmembrane transporter activity IDA
 molecular_functionGO:0015491 cation:cation antiporter activity IBA
 molecular_functionGO:0022857 transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Import of palmitoyl-CoA into the mitochondrial matrix
Organic cation transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sirt2tm1a(EUCOMM)Wtsi/Sirt2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0009199 abnormal external male genitalia morphology "any structural anomaly of the external masculine genital organs, including the penis and scrotum" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd
Genetic Background: C57BL/6N-Otud7btm1(NCOM)Cmhd/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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