ENSDARG00000030881


Danio rerio

Features
Gene ID: ENSDARG00000030881
  
Biological name :baxb
  
Synonyms : baxb / BCL2 associated X, apoptosis regulator b
  
Possible biological names infered from orthology : Apoptosis regulator BAX / BAX / BCL2 associated X, apoptosis regulator / Q07812 / Q07813
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 32074806
Gene end: 32079916
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000040899
swissprot - F1QTZ0
ZFIN ID - ZDB-GENE-050227-21
Ensembl - ENSDARG00000030881
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BAXENSG00000087088Homo sapiens
 BaxENSMUSG00000003873Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BX511080.1 / BAX* / Q07812* / BCL2 associated X, apoptosis regulator*ENSDARG0000008999530
baxa / BCL2 associated X, apoptosis regulator a / BAX* / Q07813* / Q07812* / Apoptosis regulator BAX * / BCL2 associated X, apoptosis regulator*ENSDARG0000002062322
zgc:153993ENSDARG0000009972218
baxa / BCL2 associated X, apoptosis regulator a / BAX* / Q07813* / Q07812* / Apoptosis regulator BAX * / BCL2 associated X, apoptosis regulator*ENSDARG0000008912916


Protein motifs (from Interpro)
Interpro ID Name
 IPR002475  Bcl2-like
 IPR026298  Blc2 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001836 release of cytochrome c from mitochondria IBA
 biological_processGO:0008053 mitochondrial fusion IBA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IBA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IGI
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IBA
 cellular_componentGO:0005741 mitochondrial outer membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0015267 channel activity IBA
 molecular_functionGO:0042803 protein homodimerization activity IBA
 molecular_functionGO:0046982 protein heterodimerization activity IBA


Pathways (from Reactome)
Pathway description
Release of apoptotic factors from the mitochondria
Activation, translocation and oligomerization of BAX
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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