ENSDARG00000089129


Danio rerio

Features
Gene ID: ENSDARG00000089129
  
Biological name :baxa
  
Synonyms : baxa / BCL2 associated X, apoptosis regulator a
  
Possible biological names infered from orthology : Apoptosis regulator BAX / BAX / BCL2 associated X, apoptosis regulator / Q07812 / Q07813
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 37766473
Gene end: 37773800
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000108051
Ensembl peptide - ENSDARP00000126185
NCBI entrez gene - 100004321     See in Manteia.
RefSeq - NM_001328066
RefSeq Peptide - NP_001314995
swissprot - I3ITC2
swissprot - E7F9W2
ZFIN ID - ZDB-GENE-000511-6
Ensembl - ENSDARG00000089129
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BAXENSG00000087088Homo sapiens
 BaxENSMUSG00000003873Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
baxa / BCL2 associated X, apoptosis regulator a / BAX* / Q07813* / Q07812* / Apoptosis regulator BAX * / BCL2 associated X, apoptosis regulator*ENSDARG0000002062352
zgc:153993ENSDARG0000009972225
baxb / BCL2 associated X, apoptosis regulator b / BAX* / Q07813* / Q07812* / Apoptosis regulator BAX * / BCL2 associated X, apoptosis regulator*ENSDARG0000003088117
BX511080.1 / BAX* / Q07812* / BCL2 associated X, apoptosis regulator*ENSDARG0000008999512


Protein motifs (from Interpro)
Interpro ID Name
 IPR002475  Bcl2-like
 IPR026298  Blc2 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001836 release of cytochrome c from mitochondria IBA
 biological_processGO:0008053 mitochondrial fusion IBA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IBA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
 biological_processGO:0046686 response to cadmium ion IEP
 biological_processGO:0051597 response to methylmercury IDA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IBA
 cellular_componentGO:0005741 mitochondrial outer membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0015267 channel activity IBA
 molecular_functionGO:0042803 protein homodimerization activity IBA
 molecular_functionGO:0046982 protein heterodimerization activity IBA


Pathways (from Reactome)
Pathway description
Release of apoptotic factors from the mitochondria
Activation, translocation and oligomerization of BAX
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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