ENSDARG00000031737


Danio rerio

Features
Gene ID: ENSDARG00000031737
  
Biological name :pthlha
  
Synonyms : parathyroid hormone-like hormone a / pthlha
  
Possible biological names infered from orthology : P12272 / parathyroid hormone like hormone / parathyroid hormone-like peptide / PTHLH
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 612363
Gene end: 626550
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000049153
Ensembl peptide - ENSDARP00000143652
NCBI entrez gene - 554221     See in Manteia.
RefSeq - NM_001024627
RefSeq Peptide - NP_001019798
swissprot - Q5SPK3
ZFIN ID - ZDB-GENE-050119-9
Ensembl - ENSDARG00000031737
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTHLHENSGALG00000017295Gallus gallus
 PTHLHENSG00000087494Homo sapiens
 PthlhENSMUSG00000048776Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pthlhb / parathyroid hormone-like hormone b / PTHLH* / P12272* / parathyroid hormone like hormone* / parathyroid hormone-like peptide*ENSDARG0000007107033


Protein motifs (from Interpro)
Interpro ID Name
 IPR001415  Parathyroid hormone/parathyroid hormone-related protein
 IPR003626  Parathyroid hormone-related protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002076 osteoblast development IBA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030282 bone mineralization IEA
 biological_processGO:0032330 regulation of chondrocyte differentiation IBA
 biological_processGO:0035907 dorsal aorta development IMP
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005179 hormone activity IBA
 molecular_functionGO:0051428 peptide hormone receptor binding IBA


Pathways (from Reactome)
Pathway description
Class B/2 (Secretin family receptors)
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000014 dorsal aorta dorsal aorta closed , abnormal
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 ZFA:0000031 hypochord hypochord Notch signaling pathway decreased process quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000020957 pth1ra / parathyroid hormone 1 receptor a / PTH1R* / Q03431* / P41593* / parathyroid hormone 1 receptor* / Parathyroid hormone/parathyroid hormone-related peptide receptor *  / reaction / complex






 

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