ENSGALG00000017295


Gallus gallus

Features
Gene ID: ENSGALG00000017295
  
Biological name :PTHLH
  
Synonyms : P17251 / Parathyroid hormone-related protein Osteostatin / PTHLH
  
Possible biological names infered from orthology : P12272 / parathyroid hormone like hormone / parathyroid hormone-like peptide
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 72518738
Gene end: 72529849
  
Corresponding Affymetrix probe sets: Gga.2626.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000029396
Ensembl peptide - ENSGALP00000048574
Ensembl peptide - ENSGALP00000055214
Ensembl peptide - ENSGALP00000064203
NCBI entrez gene - 396281     See in Manteia.
RefSeq - XM_015292186
RefSeq - NM_001174106
RefSeq - NM_205338
RefSeq - XM_015292173
RefSeq Peptide - NP_001167577
RefSeq Peptide - NP_990669
swissprot - P17251
swissprot - Q5TLZ2
Ensembl - ENSGALG00000017295
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pthlhaENSDARG00000031737Danio rerio
 pthlhbENSDARG00000071070Danio rerio
 PTHLHENSG00000087494Homo sapiens
 PthlhENSMUSG00000048776Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001415  Parathyroid hormone/parathyroid hormone-related protein
 IPR003626  Parathyroid hormone-related protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0002076 osteoblast development IBA
 biological_processGO:0003420 regulation of growth plate cartilage chondrocyte proliferation IMP
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030282 bone mineralization IEA
 biological_processGO:0030819 obsolete positive regulation of cAMP biosynthetic process IEA
 biological_processGO:0032330 regulation of chondrocyte differentiation IBA
 biological_processGO:0032331 negative regulation of chondrocyte differentiation IEA
 biological_processGO:1902733 regulation of growth plate cartilage chondrocyte differentiation IMP
 biological_processGO:1903042 negative regulation of chondrocyte hypertrophy IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0005179 hormone activity IBA
 molecular_functionGO:0051428 peptide hormone receptor binding IBA


Pathways (from Reactome)
Pathway description
Class B/2 (Secretin family receptors)
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000005476 PTH1R / parathyroid hormone 1 receptor / P41593* / Q03431* / Parathyroid hormone/parathyroid hormone-related peptide receptor *  / reaction / complex






 

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