ENSDARG00000032237


Danio rerio

Features
Gene ID: ENSDARG00000032237
  
Biological name :anapc4
  
Synonyms : anapc4 / anaphase promoting complex subunit 4
  
Possible biological names infered from orthology : Q91W96 / Q9UJX5
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 23475381
Gene end: 23494712
  
Corresponding Affymetrix probe sets: Dr.9164.1.A1_at (Zebrafish Array)   Dr.9164.2.S1_at (Zebrafish Array)   NM_001008589_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000058523
Ensembl peptide - ENSDARP00000120188
NCBI entrez gene - 494046     See in Manteia.
RefSeq - NM_001008589
RefSeq - XM_009294660
RefSeq Peptide - NP_001008589
swissprot - Q5PR93
swissprot - F6NLM6
ZFIN ID - ZDB-GENE-041212-10
Ensembl - ENSDARG00000032237
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000040439Gallus gallus
 ENSGALG00000014378Gallus gallus
 ANAPC4ENSG00000053900Homo sapiens
 Anapc4ENSMUSG00000029176Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017169  Anaphase-promoting complex subunit 4, metazoa
 IPR024789  Anaphase-promoting complex subunit 4
 IPR024790  Anaphase-promoting complex subunit 4 long domain
 IPR024977  Anaphase-promoting complex subunit 4, WD40 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030071 regulation of mitotic metaphase/anaphase transition IEA
 biological_processGO:0031145 anaphase-promoting complex-dependent catabolic process IEA
 cellular_componentGO:0005680 anaphase-promoting complex IEA


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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