ENSDARG00000032553


Danio rerio

Features
Gene ID: ENSDARG00000032553
  
Biological name :egln3
  
Synonyms : egl-9 family hypoxia-inducible factor 3 / egln3
  
Possible biological names infered from orthology : Q9H6Z9
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 9912036
Gene end: 9936915
  
Corresponding Affymetrix probe sets: Dr.9457.1.A1_at (Zebrafish Array)   NM_213310_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000124991
Ensembl peptide - ENSDARP00000123982
NCBI entrez gene - 406602     See in Manteia.
RefSeq - NM_213310
RefSeq Peptide - NP_998475
swissprot - F8W5S7
swissprot - F8W461
ZFIN ID - ZDB-GENE-040426-2541
Ensembl - ENSDARG00000032553
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EGLN3ENSGALG00000010001Gallus gallus
 EGLN3ENSG00000129521Homo sapiens
 Egln3ENSMUSG00000035105Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
egln1b / egl-9 family hypoxia-inducible factor 1b / EGLN1* / Q91YE3* / Q9GZT9* / Egl nine homolog 1 * / egl-9 family hypoxia inducible factor 1*ENSDARG0000000463256
egln1a / egl-9 family hypoxia-inducible factor 1a / EGLN1* / Q91YE3* / Q9GZT9* / Egl nine homolog 1 * / egl-9 family hypoxia inducible factor 1*ENSDARG0000003899655
egln2 / egl-9 family hypoxia-inducible factor 2 / Q96KS0* / Q91YE2* / AC008537.1* / Egl nine homolog 2 *ENSDARG0000006256249
egln1b / egl-9 family hypoxia-inducible factor 1b / EGLN1* / Q91YE3* / Q9GZT9* / Egl nine homolog 1 * / egl-9 family hypoxia inducible factor 1*ENSDARG0000010515619


Protein motifs (from Interpro)
Interpro ID Name
 IPR005123  Oxoglutarate/iron-dependent dioxygenase
 IPR006620  Prolyl 4-hydroxylase, alpha subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0031418 L-ascorbic acid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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