ENSDARG00000034693


Danio rerio

Features
Gene ID: ENSDARG00000034693
  
Biological name :mysm1
  
Synonyms : Myb-like, SWIRM and MPN domains 1 / mysm1 / Q5RGA4
  
Possible biological names infered from orthology : Histone H2A deubiquitinase MYSM1 / Q5VVJ2 / Q69Z66
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 9093366
Gene end: 9123296
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000107103
Ensembl peptide - ENSDARP00000148580
NCBI entrez gene - 561225     See in Manteia.
RefSeq - NM_001164029
RefSeq Peptide - NP_001157501
swissprot - Q5RGA4
ZFIN ID - ZDB-GENE-041014-28
Ensembl - ENSDARG00000034693
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYSM1ENSGALG00000010869Gallus gallus
 MYSM1ENSG00000162601Homo sapiens
 Mysm1ENSMUSG00000062627Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mpnd / Q08CH3 / MPN domain containing / Q8N594* / Q3TV65* / MPN domain-containing protein *ENSDARG0000006198911


Protein motifs (from Interpro)
Interpro ID Name
 IPR000555  JAB1/MPN/MOV34 metalloenzyme domain
 IPR001005  SANT/Myb domain
 IPR007526  SWIRM domain
 IPR009057  Homeobox-like domain superfamily
 IPR011991  ArsR-like helix-turn-helix domain
 IPR017884  SANT domain
 IPR033497  Histone H2A deubiquitinase MYSM1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006338 chromatin remodeling ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0035522 monoubiquitinated histone H2A deubiquitination ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:1904888 cranial skeletal system development IMP
 cellular_componentGO:0005634 nucleus ISS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003713 transcription coactivator activity ISS
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity ISS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity ISS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity ISS
 molecular_functionGO:0042393 histone binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000084 yolk yolk deformed , abnormal
Show

 ZFA:0000106 extension extension decreased length , abnormal
Show

 ZFA:0000107 eye eye malformed , abnormal
Show

 ZFA:0000135 notochord notochord malformed , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curled , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage morphology , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton decreased size , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr