ENSG00000162601


Homo sapiens

Features
Gene ID: ENSG00000162601
  
Biological name :MYSM1
  
Synonyms : Myb like, SWIRM and MPN domains 1 / MYSM1 / Q5VVJ2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p32.1
Gene start: 58654739
Gene end: 58700092
  
Corresponding Affymetrix probe sets: 1569706_at (Human Genome U133 Plus 2.0 Array)   225760_at (Human Genome U133 Plus 2.0 Array)   238644_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418734
Ensembl peptide - ENSP00000478391
NCBI entrez gene - 114803     See in Manteia.
OMIM - 612176
RefSeq - XM_017000197
RefSeq - NM_001085487
RefSeq - XM_017000195
RefSeq - XM_017000196
RefSeq - XM_006710314
RefSeq - XM_011540573
RefSeq - XM_011540574
RefSeq Peptide - NP_001078956
swissprot - Q5VVJ2
Ensembl - ENSG00000162601
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mysm1ENSDARG00000034693Danio rerio
 MYSM1ENSGALG00000010869Gallus gallus
 Mysm1ENSMUSG00000062627Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MPND / Q8N594 / MPN domain containingENSG0000000838213


Protein motifs (from Interpro)
Interpro ID Name
 IPR000555  JAB1/MPN/MOV34 metalloenzyme domain
 IPR001005  SANT/Myb domain
 IPR007526  SWIRM domain
 IPR009057  Homeobox-like domain superfamily
 IPR017884  SANT domain
 IPR033497  Histone H2A deubiquitinase MYSM1
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR037518  MPN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006338 chromatin remodeling IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0030334 regulation of cell migration IEA
 biological_processGO:0035522 monoubiquitinated histone H2A deubiquitination IMP
 biological_processGO:0043473 pigmentation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0051797 regulation of hair follicle development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IDA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IMP
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IDA
 molecular_functionGO:0042393 histone binding IDA
 molecular_functionGO:0044877 protein-containing complex binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Metalloprotease DUBs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000114166 KAT2B / Q92831 / lysine acetyltransferase 2B  / complex
 ENSG00000100393 EP300 / Q09472 / E1A binding protein p300  / complex






 

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