ENSDARG00000035452


Danio rerio

Features
Gene ID: ENSDARG00000035452
  
Biological name :camkk1a
  
Synonyms : calcium/calmodulin-dependent protein kinase kinase 1, alpha a / camkk1a
  
Possible biological names infered from orthology : calcium/calmodulin dependent protein kinase kinase 1 / CAMKK1 / Q8N5S9 / Q8VBY2
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 31283576
Gene end: 31432727
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000029907
Ensembl peptide - ENSDARP00000122850
NCBI entrez gene - 541526     See in Manteia.
swissprot - A2BIP2
swissprot - Q58EH5
ZFIN ID - ZDB-GENE-050327-62
Ensembl - ENSDARG00000035452
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CAMKK1ENSGALG00000001617Gallus gallus
 CAMKK1ENSG00000004660Homo sapiens
 Camkk1ENSMUSG00000020785Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
camkk1b / calcium/calmodulin-dependent protein kinase kinase 1, alpha b / CAMKK1* / Q8N5S9* / Q8VBY2* / calcium/calmodulin dependent protein kinase kinase 1*ENSDARG0000001513466
si:ch73-62l21.1 / CAMKK2* / Q8C078* / Q96RR4* / calcium/calmodulin dependent protein kinase kinase 2*ENSDARG0000007864539
stk11 / serine/threonine kinase 11 / Q15831* / Q9WTK7* / Serine/threonine-protein kinase STK11 *ENSDARG0000004607423


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR020636  Calcium/calmodulin-dependent/calcium-dependent protein kinase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0045860 positive regulation of protein kinase activity IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004683 calmodulin-dependent protein kinase activity IBA
 molecular_functionGO:0005516 calmodulin binding IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
CREB phosphorylation through the activation of CaMKK


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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