ENSG00000004660


Homo sapiens

Features
Gene ID: ENSG00000004660
  
Biological name :CAMKK1
  
Synonyms : calcium/calmodulin dependent protein kinase kinase 1 / CAMKK1 / Q8N5S9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.2
Gene start: 3860315
Gene end: 3894891
  
Corresponding Affymetrix probe sets: 1552768_at (Human Genome U133 Plus 2.0 Array)   223460_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000158166
Ensembl peptide - ENSP00000323118
Ensembl peptide - ENSP00000371188
NCBI entrez gene - 84254     See in Manteia.
OMIM - 611411
RefSeq - XM_017025220
RefSeq - NM_032294
RefSeq - NM_172206
RefSeq - NM_172207
RefSeq - XM_005256817
RefSeq - XM_006721588
RefSeq - XM_011524031
RefSeq - XM_011524033
RefSeq - XM_017025219
RefSeq Peptide - NP_115670
RefSeq Peptide - NP_757343
RefSeq Peptide - NP_757344
swissprot - Q8N5S9
swissprot - J3KPJ3
Ensembl - ENSG00000004660
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 camkk1aENSDARG00000035452Danio rerio
 camkk1bENSDARG00000015134Danio rerio
 CAMKK1ENSGALG00000001617Gallus gallus
 Camkk1ENSMUSG00000020785Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CAMKK2 / Q96RR4 / calcium/calmodulin dependent protein kinase kinase 2ENSG0000011093156
STK11 / Q15831 / serine/threonine kinase 11ENSG0000011804623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0045860 positive regulation of protein kinase activity IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004683 calmodulin-dependent protein kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
CREB phosphorylation through the activation of CaMKK


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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