ENSDARG00000035835


Danio rerio

Features
Gene ID: ENSDARG00000035835
  
Biological name :eef2k
  
Synonyms : eef2k / eukaryotic elongation factor 2 kinase
  
Possible biological names infered from orthology : O00418 / O08796
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 10381957
Gene end: 10409970
  
Corresponding Affymetrix probe sets: Dr.523.1.A1_at (Zebrafish Array)   NM_001002740_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000124692
Ensembl peptide - ENSDARP00000052000
NCBI entrez gene - 437013     See in Manteia.
RefSeq - NM_001002740
RefSeq Peptide - NP_001002740
swissprot - E7F318
swissprot - Q6DGE0
ZFIN ID - ZDB-GENE-020916-2
Ensembl - ENSDARG00000035835
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EEF2KENSGALG00000006982Gallus gallus
 EEF2KENSG00000103319Homo sapiens
 Eef2kENSMUSG00000035064Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004166  MHCK/EF2 kinase
 IPR006597  Sel1-like repeat
 IPR011009  Protein kinase-like domain superfamily
 IPR017400  Eukaryotic elongation factor 2 kinase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006414 translational elongation IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0061300 cerebellum vasculature development IGI
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003746 translation elongation factor activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0004686 elongation factor-2 kinase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
mTORC1-mediated signalling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001267 cranial vasculature cranial vasculature structure , ameliorated
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018399 rps6kb1a / ribosomal protein S6 kinase b, polypeptide 1a / Q8BSK8* / P23443* / RPS6KB1* / ribosomal protein S6 kinase B1* / ribosomal protein S6 kinase, polypeptide 1*  / reaction
 ENSDARG00000058230 rps6kb1b / ribosomal protein S6 kinase b, polypeptide 1b / Q8BSK8* / P23443* / RPS6KB1* / ribosomal protein S6 kinase B1* / ribosomal protein S6 kinase, polypeptide 1*  / reaction






 

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