ENSDARG00000058230


Danio rerio

Features
Gene ID: ENSDARG00000058230
  
Biological name :rps6kb1b
  
Synonyms : ribosomal protein S6 kinase b, polypeptide 1b / rps6kb1b
  
Possible biological names infered from orthology : P23443 / Q8BSK8 / ribosomal protein S6 kinase B1 / ribosomal protein S6 kinase, polypeptide 1 / RPS6KB1
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 17406920
Gene end: 17424590
  
Corresponding Affymetrix probe sets: Dr.24528.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000075502
swissprot - F1R3V1
ZFIN ID - ZDB-GENE-040426-2038
Ensembl - ENSDARG00000058230
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RPS6KB1ENSGALG00000005198Gallus gallus
 P23443ENSG00000108443Homo sapiens
 Q8BSK8ENSMUSG00000020516Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rps6kb1a / ribosomal protein S6 kinase b, polypeptide 1a / Q8BSK8* / P23443* / RPS6KB1* / ribosomal protein S6 kinase B1* / ribosomal protein S6 kinase, polypeptide 1*ENSDARG0000001839981
rps6ka3a / ribosomal protein S6 kinase a, polypeptide 3aENSDARG0000003555643
rps6ka3b / ribosomal protein S6 kinase, polypeptide 3bENSDARG0000005792742
rps6ka2 / ribosomal protein S6 kinase, polypeptide 2 / Q15349* / ribosomal protein S6 kinase A2*ENSDARG0000002846942
rps6kal / ribosomal protein S6 kinase a, like / Q9UK32* / RPS6KA6* / ribosomal protein S6 kinase A6* / ribosomal protein S6 kinase polypeptide 6*ENSDARG0000003757441
rps6ka1 / ribosomal protein S6 kinase a, polypeptide 1 / P18653* / Q15418* / ribosomal protein S6 kinase A1* / ribosomal protein S6 kinase polypeptide 1*ENSDARG0000003343741
rps6ka4 / ribosomal protein S6 kinase, polypeptide 4 / O75676* / Q9Z2B9* / ribosomal protein S6 kinase A4*ENSDARG0000004443639
rps6ka5 / ribosomal protein S6 kinase, polypeptide 5 / O75582* / Q8C050* / ribosomal protein S6 kinase A5*ENSDARG0000006055138
stk32a / serine/threonine kinase 32A / Q8BGW6* / Q8WU08* / Serine/threonine-protein kinase 32A *ENSDARG0000007949912


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR016238  Ribosomal protein S6 kinase
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0045948 positive regulation of translational initiation IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
mTORC1-mediated signalling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000019778 rps6 / ribosomal protein S6 / P62753* / P62754* / 40S ribosomal protein S6 *  / reaction
 ENSDARG00000035835 eef2k / eukaryotic elongation factor 2 kinase / O00418* / O08796*  / reaction






 

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