ENSDARG00000037574


Danio rerio

Features
Gene ID: ENSDARG00000037574
  
Biological name :rps6kal
  
Synonyms : ribosomal protein S6 kinase a, like / rps6kal
  
Possible biological names infered from orthology : Q9UK32 / ribosomal protein S6 kinase A6 / ribosomal protein S6 kinase polypeptide 6 / RPS6KA6
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 8940326
Gene end: 9002405
  
Corresponding Affymetrix probe sets: Dr.811.1.S1_at (Zebrafish Array)   NM_200073_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000130163
Ensembl peptide - ENSDARP00000141678
NCBI entrez gene - 337670     See in Manteia.
RefSeq - NM_200073
RefSeq Peptide - NP_956367
swissprot - A0A0R4IZP9
swissprot - A0A0R4ICF4
ZFIN ID - ZDB-GENE-030131-9616
Ensembl - ENSDARG00000037574
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RPS6KA6ENSGALG00000007097Gallus gallus
 Q9UK32ENSG00000072133Homo sapiens
 Rps6ka6ENSMUSG00000025665Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rps6ka3a / ribosomal protein S6 kinase a, polypeptide 3aENSDARG0000003555677
rps6ka3b / ribosomal protein S6 kinase, polypeptide 3bENSDARG0000005792775
rps6ka2 / ribosomal protein S6 kinase, polypeptide 2 / Q15349* / ribosomal protein S6 kinase A2*ENSDARG0000002846975
rps6ka1 / ribosomal protein S6 kinase a, polypeptide 1 / P18653* / Q15418* / ribosomal protein S6 kinase A1* / ribosomal protein S6 kinase polypeptide 1*ENSDARG0000003343774
rps6ka5 / ribosomal protein S6 kinase, polypeptide 5 / O75582* / Q8C050* / ribosomal protein S6 kinase A5*ENSDARG0000006055141
rps6ka4 / ribosomal protein S6 kinase, polypeptide 4 / O75676* / Q9Z2B9* / ribosomal protein S6 kinase A4*ENSDARG0000004443641
rps6kb1a / ribosomal protein S6 kinase b, polypeptide 1a / Q8BSK8* / P23443* / RPS6KB1* / ribosomal protein S6 kinase B1* / ribosomal protein S6 kinase, polypeptide 1*ENSDARG0000001839928
rps6kb1b / ribosomal protein S6 kinase b, polypeptide 1b / Q8BSK8* / P23443* / RPS6KB1* / ribosomal protein S6 kinase B1* / ribosomal protein S6 kinase, polypeptide 1*ENSDARG0000005823028
stk32a / serine/threonine kinase 32A / Q8BGW6* / Q8WU08* / Serine/threonine-protein kinase 32A *ENSDARG000000794999


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR016239  Ribosomal protein S6 kinase II
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
CREB phosphorylation through the activation of Ras
RSK activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018285 pdpk1b / 3-phosphoinositide dependent protein kinase 1b / PDPK1* / O15530* / Q9Z2A0* / 3-phosphoinositide dependent protein kinase 1*  / reaction
 ENSDARG00000027552 mapk1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr