ENSGALG00000007097


Gallus gallus

Features
Gene ID: ENSGALG00000007097
  
Biological name :RPS6KA6
  
Synonyms : ribosomal protein S6 kinase A6 / RPS6KA6
  
Possible biological names infered from orthology : Q9UK32 / ribosomal protein S6 kinase polypeptide 6
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 9026243
Gene end: 9061303
  
Corresponding Affymetrix probe sets: GgaAffx.4438.1.S1_at (Chicken Array)   GgaAffx.4438.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000011476
NCBI entrez gene - 422273     See in Manteia.
RefSeq - XM_015278512
RefSeq - XM_015278513
RefSeq - XM_015278514
RefSeq - XM_015278515
RefSeq - XM_015278516
RefSeq - XM_420257
RefSeq - XM_015278511
swissprot - E1C7L2
Ensembl - ENSGALG00000007097
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rps6kalENSDARG00000037574Danio rerio
 Q9UK32ENSG00000072133Homo sapiens
 Rps6ka6ENSMUSG00000025665Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RPS6KA3 / ribosomal protein S6 kinase A3 / P18654* / P51812* / ribosomal protein S6 kinase polypeptide 3*ENSGALG0000001640679
P18652 / RPS6KA1L / Ribosomal protein S6 kinase 2 alpha / Q15418* / P18653* / RPS6KA1* / ribosomal protein S6 kinase A1* / ribosomal protein S6 kinase polypeptide 1*ENSGALG0000003713677
RPS6KA2 / ribosomal protein S6 kinase A2 / Q15349* / Q9WUT3* / ribosomal protein S6 kinase, polypeptide 2*ENSGALG0000001147377
Q5F3L1 / RPS6KA5 / Ribosomal protein S6 kinase alpha-5 / Q8C050* / O75582* / ribosomal protein S6 kinase A5* / ribosomal protein S6 kinase, polypeptide 5*ENSGALG0000003058041
RPS6KB1 / ribosomal protein S6 kinase beta-1 / P23443* / Q8BSK8* / ribosomal protein S6 kinase B1* / ribosomal protein S6 kinase, polypeptide 1*ENSGALG0000000519828
STK32C / serine/threonine kinase 32C / Q86UX6* / Q8QZV4* / Serine/threonine-protein kinase 32C *ENSGALG0000002061517
STK32A / serine/threonine kinase 32A / Q8BGW6* / Q8WU08* / Serine/threonine-protein kinase 32A *ENSGALG0000002919516
STK32B / serine/threonine kinase 32B / Q9JJX8* / Q9NY57* / Serine/threonine-protein kinase 32B *ENSGALG0000002951016


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR016239  Ribosomal protein S6 kinase II
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
CREB phosphorylation through the activation of Ras
RSK activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001501 MAPK1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*  / reaction
 ENSGALG00000006418 PDPK1 / 3-phosphoinositide dependent protein kinase 1 / O15530* / Q9Z2A0*  / reaction
 ENSGALG00000008494 CREB1 / P16220* / Q01147* / cAMP responsive element binding protein 1* / Cyclic AMP-responsive element-binding protein 1 *  / reaction






 

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