ENSGALG00000008494


Gallus gallus

Features
Gene ID: ENSGALG00000008494
  
Biological name :CREB1
  
Synonyms : CREB1
  
Possible biological names infered from orthology : cAMP responsive element binding protein 1 / Cyclic AMP-responsive element-binding protein 1 / P16220 / Q01147
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 12239757
Gene end: 12275487
  
Corresponding Affymetrix probe sets: Gga.3025.1.S1_at (Chicken Array)   Gga.8529.1.S1_at (Chicken Array)   Gga.8529.1.S1_s_at (Chicken Array)   Gga.8529.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000064675
Ensembl peptide - ENSGALP00000013824
NCBI entrez gene - 395099     See in Manteia.
RefSeq - XM_015289373
RefSeq - NM_204450
RefSeq - XM_015289371
RefSeq - XM_015289372
RefSeq Peptide - NP_989781
swissprot - A0A1L1S0L6
swissprot - Q7SX83
Ensembl - ENSGALG00000008494
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 creb1aENSDARG00000053586Danio rerio
 creb1bENSDARG00000093420Danio rerio
 CREB1ENSG00000118260Homo sapiens
 Creb1ENSMUSG00000025958Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATF1* / P18846* / P81269* / activating transcription factor 1* / Cyclic AMP-dependent transcription factor ATF-1 *ENSGALG0000003361459
CREM / cAMP-responsive element modulator isoform 5 / P27699* / Q03060* / cAMP responsive element modulator*ENSGALG0000000708252


Protein motifs (from Interpro)
Interpro ID Name
 IPR001630  cAMP response element binding (CREB) protein
 IPR003102  Coactivator CBP, pKID
 IPR004827  Basic-leucine zipper domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
AKT phosphorylates targets in the nucleus
CREB phosphorylation
NCAM signaling for neurite out-growth
CREB phosphorylation through the activation of CaMKK
CREB phosphorylation through the activation of Adenylate Cyclase
CREB phosphorylation through the activation of CaMKII
CREB phosphorylation through the activation of Ras
Gastrin-CREB signalling pathway via PKC and MAPK


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000883 MAPKAPK2 / mitogen-activated protein kinase-activated protein kinase 2 / P49137* / P49138* / MAP kinase-activated protein kinase 2 *  / reaction
 ENSGALG00000005621 CAMK2A / calcium/calmodulin-dependent protein kinase type II subunit alpha / P11798* / Q9UQM7* / calcium/calmodulin dependent protein kinase II alpha*  / reaction
 ENSGALG00000007097 RPS6KA6 / ribosomal protein S6 kinase A6 / Q9UK32* / ribosomal protein S6 kinase polypeptide 6*  / reaction
 ENSGALG00000010023 CALM2 / P62149 / Calmodulin / Calm3* / CALM1* / P0DP23* / P0DP26* / P0DP27* / P0DP28* / calmodulin 1*  / reaction
 ENSGALG00000037136 P18652 / RPS6KA1L / Ribosomal protein S6 kinase 2 alpha / Q15418* / P18653* / RPS6KA1* / ribosomal protein S6 kinase A1* / ribosomal protein S6 kinase polypeptide 1*  / reaction
 ENSGALG00000030580 Q5F3L1 / RPS6KA5 / Ribosomal protein S6 kinase alpha-5 / Q8C050* / O75582* / ribosomal protein S6 kinase A5* / ribosomal protein S6 kinase, polypeptide 5*  / reaction






 

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