ENSGALG00000011473


Gallus gallus

Features
Gene ID: ENSGALG00000011473
  
Biological name :RPS6KA2
  
Synonyms : ribosomal protein S6 kinase A2 / RPS6KA2
  
Possible biological names infered from orthology : Q15349 / Q9WUT3 / ribosomal protein S6 kinase, polypeptide 2
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 42718416
Gene end: 42955179
  
Corresponding Affymetrix probe sets: GgaAffx.7275.1.S1_at (Chicken Array)   GgaAffx.7275.2.S1_at (Chicken Array)   GgaAffx.7275.2.S1_s_at (Chicken Array)   GgaAffx.7275.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018680
NCBI entrez gene - 421570     See in Manteia.
RefSeq - XM_419611
swissprot - F1P1H2
Ensembl - ENSGALG00000011473
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rps6ka2ENSDARG00000028469Danio rerio
 Q15349ENSG00000071242Homo sapiens
 Q9WUT3ENSMUSG00000023809Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RPS6KA3 / ribosomal protein S6 kinase A3 / P18654* / P51812* / ribosomal protein S6 kinase polypeptide 3*ENSGALG0000001640682
RPS6KA6 / ribosomal protein S6 kinase A6 / Q9UK32* / ribosomal protein S6 kinase polypeptide 6*ENSGALG0000000709780
P18652 / RPS6KA1L / Ribosomal protein S6 kinase 2 alpha / Q15418* / P18653* / RPS6KA1* / ribosomal protein S6 kinase A1* / ribosomal protein S6 kinase polypeptide 1*ENSGALG0000003713680
Q5F3L1 / RPS6KA5 / Ribosomal protein S6 kinase alpha-5 / Q8C050* / O75582* / ribosomal protein S6 kinase A5* / ribosomal protein S6 kinase, polypeptide 5*ENSGALG0000003058043
RPS6KB1 / ribosomal protein S6 kinase beta-1 / P23443* / Q8BSK8* / ribosomal protein S6 kinase B1* / ribosomal protein S6 kinase, polypeptide 1*ENSGALG0000000519829
STK32B / serine/threonine kinase 32B / Q9JJX8* / Q9NY57* / Serine/threonine-protein kinase 32B *ENSGALG0000002951017
STK32C / serine/threonine kinase 32C / Q86UX6* / Q8QZV4* / Serine/threonine-protein kinase 32C *ENSGALG0000002061517
STK32A / serine/threonine kinase 32A / Q8BGW6* / Q8WU08* / Serine/threonine-protein kinase 32A *ENSGALG0000002919516


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR016239  Ribosomal protein S6 kinase II
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001556 oocyte maturation IEA
 biological_processGO:0002035 brain renin-angiotensin system IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010659 cardiac muscle cell apoptotic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0045835 negative regulation of meiotic nuclear division IEA
 biological_processGO:0060047 heart contraction IEA
 biological_processGO:0070613 regulation of protein processing IEA
 biological_processGO:0071322 cellular response to carbohydrate stimulus IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0004711 ribosomal protein S6 kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
ERK/MAPK targets
CREB phosphorylation
Senescence-Associated Secretory Phenotype (SASP)
CREB phosphorylation through the activation of Ras
RSK activation
Gastrin-CREB signalling pathway via PKC and MAPK


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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