ENSDARG00000033437


Danio rerio

Features
Gene ID: ENSDARG00000033437
  
Biological name :rps6ka1
  
Synonyms : ribosomal protein S6 kinase a, polypeptide 1 / rps6ka1
  
Possible biological names infered from orthology : P18653 / Q15418 / ribosomal protein S6 kinase A1 / ribosomal protein S6 kinase polypeptide 1
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 27064158
Gene end: 27172352
  
Corresponding Affymetrix probe sets: Dr.21796.1.A1_at (Zebrafish Array)   Dr.26049.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000147972
Ensembl peptide - ENSDARP00000151674
Ensembl peptide - ENSDARP00000044377
Ensembl peptide - ENSDARP00000104901
Ensembl peptide - ENSDARP00000126409
Ensembl peptide - ENSDARP00000126449
Ensembl peptide - ENSDARP00000144319
NCBI entrez gene - 777728     See in Manteia.
swissprot - A0A286YAW9
swissprot - F1QYQ1
swissprot - F1RAV5
swissprot - K7DY81
swissprot - K7DYC0
swissprot - Q08CV8
ZFIN ID - ZDB-GENE-060929-516
Ensembl - ENSDARG00000033437
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P18652ENSGALG00000037136Gallus gallus
 Q15418ENSG00000117676Homo sapiens
 P18653ENSMUSG00000003644Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rps6ka2 / ribosomal protein S6 kinase, polypeptide 2 / Q15349* / ribosomal protein S6 kinase A2*ENSDARG0000002846974
rps6ka3a / ribosomal protein S6 kinase a, polypeptide 3aENSDARG0000003555674
rps6kal / ribosomal protein S6 kinase a, like / Q9UK32* / RPS6KA6* / ribosomal protein S6 kinase A6* / ribosomal protein S6 kinase polypeptide 6*ENSDARG0000003757472
rps6ka3b / ribosomal protein S6 kinase, polypeptide 3bENSDARG0000005792772
rps6ka5 / ribosomal protein S6 kinase, polypeptide 5 / O75582* / Q8C050* / ribosomal protein S6 kinase A5*ENSDARG0000006055139
rps6ka4 / ribosomal protein S6 kinase, polypeptide 4 / O75676* / Q9Z2B9* / ribosomal protein S6 kinase A4*ENSDARG0000004443639
rps6kb1b / ribosomal protein S6 kinase b, polypeptide 1b / Q8BSK8* / P23443* / RPS6KB1* / ribosomal protein S6 kinase B1* / ribosomal protein S6 kinase, polypeptide 1*ENSDARG0000005823027
rps6kb1a / ribosomal protein S6 kinase b, polypeptide 1a / Q8BSK8* / P23443* / RPS6KB1* / ribosomal protein S6 kinase B1* / ribosomal protein S6 kinase, polypeptide 1*ENSDARG0000001839927
stk32a / serine/threonine kinase 32A / Q8BGW6* / Q8WU08* / Serine/threonine-protein kinase 32A *ENSDARG000000794999


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR016239  Ribosomal protein S6 kinase II
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
ERK/MAPK targets
CREB phosphorylation
Senescence-Associated Secretory Phenotype (SASP)
CREB phosphorylation through the activation of Ras
RSK activation
Gastrin-CREB signalling pathway via PKC and MAPK


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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