ENSDARG00000060551


Danio rerio

Features
Gene ID: ENSDARG00000060551
  
Biological name :rps6ka5
  
Synonyms : ribosomal protein S6 kinase, polypeptide 5 / rps6ka5
  
Possible biological names infered from orthology : O75582 / Q8C050 / ribosomal protein S6 kinase A5
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 38393189
Gene end: 38442362
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000079873
NCBI entrez gene - 565173     See in Manteia.
swissprot - E7FE05
ZFIN ID - ZDB-GENE-130530-693
Ensembl - ENSDARG00000060551
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5F3L1ENSGALG00000030580Gallus gallus
 O75582ENSG00000100784Homo sapiens
 Q8C050ENSMUSG00000021180Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rps6ka4 / ribosomal protein S6 kinase, polypeptide 4 / O75676* / Q9Z2B9* / ribosomal protein S6 kinase A4*ENSDARG0000004443661
rps6ka3a / ribosomal protein S6 kinase a, polypeptide 3aENSDARG0000003555638
rps6ka2 / ribosomal protein S6 kinase, polypeptide 2 / Q15349* / ribosomal protein S6 kinase A2*ENSDARG0000002846938
rps6kal / ribosomal protein S6 kinase a, like / Q9UK32* / RPS6KA6* / ribosomal protein S6 kinase A6* / ribosomal protein S6 kinase polypeptide 6*ENSDARG0000003757438
rps6ka1 / ribosomal protein S6 kinase a, polypeptide 1 / P18653* / Q15418* / ribosomal protein S6 kinase A1* / ribosomal protein S6 kinase polypeptide 1*ENSDARG0000003343737
rps6ka3b / ribosomal protein S6 kinase, polypeptide 3bENSDARG0000005792737
rps6kb1b / ribosomal protein S6 kinase b, polypeptide 1b / Q8BSK8* / P23443* / RPS6KB1* / ribosomal protein S6 kinase B1* / ribosomal protein S6 kinase, polypeptide 1*ENSDARG0000005823024
rps6kb1a / ribosomal protein S6 kinase b, polypeptide 1a / Q8BSK8* / P23443* / RPS6KB1* / ribosomal protein S6 kinase B1* / ribosomal protein S6 kinase, polypeptide 1*ENSDARG0000001839923
stk32a / serine/threonine kinase 32A / Q8BGW6* / Q8WU08* / Serine/threonine-protein kinase 32A *ENSDARG000000794999


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR016239  Ribosomal protein S6 kinase II
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
ERK/MAPK targets
CREB phosphorylation
NCAM signaling for neurite out-growth
CD209 (DC-SIGN) signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000045836 mapk11 / mitogen-activated protein kinase 11 / Q15759* / Q9WUI1*  / reaction
 ENSDARG00000028721 mapk14b / mitogen-activated protein kinase 14b / Q16539* / MAPK14* / P47811* / mitogen-activated protein kinase 14*  / reaction
 ENSDARG00000027552 mapk1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*  / reaction
 ENSDARG00000000857 Q9DGE2 / mapk14a / mitogen-activated protein kinase 14a / P47811* / Q16539* / MAPK14* / mitogen-activated protein kinase 14*  / reaction
 ENSDARG00000105261 nfkb1 / nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 / P25799* / P19838* / nuclear factor kappa B subunit 1* / Nuclear factor NF-kappa-B p105 subunit Nuclear factor ...  / reaction
 ENSDARG00000098696 rela / v-rel avian reticuloendotheliosis viral oncogene homolog A / Q04206* / RELA proto-oncogene, NF-kB subunit*  / reaction
 ENSDARG00000044301 atf1 / activating transcription factor 1 / P18846* / P81269* / Cyclic AMP-dependent transcription factor ATF-1 *  / reaction
 ENSDARG00000070573 mapk3 / mitogen-activated protein kinase 3 / P27361* / Q63844*  / reaction






 

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