ENSDARG00000036060


Danio rerio

Features
Gene ID: ENSDARG00000036060
  
Biological name :exosc6
  
Synonyms : exosc6 / exosome component 6 / Q6P0I8
  
Possible biological names infered from orthology : Exosome complex component MTR3 / Q5RKV6 / Q8BTW3
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 29163592
Gene end: 29164818
  
Corresponding Affymetrix probe sets: Dr.6302.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000052347
NCBI entrez gene - 326786     See in Manteia.
swissprot - B2GQ67
swissprot - Q6P0I8
ZFIN ID - ZDB-GENE-050522-362
Ensembl - ENSDARG00000036060
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EXOSC6ENSG00000223496Homo sapiens
 Exosc6ENSMUSG00000109941Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
exosc4 / exosome component 4 / Q921I9* / Q9NPD3* / Exosome complex component RRP41 *ENSDARG0000010343227


Protein motifs (from Interpro)
Interpro ID Name
 IPR001247  Exoribonuclease, phosphorolytic domain 1
 IPR015847  Exoribonuclease, phosphorolytic domain 2
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR027408  PNPase/RNase PH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0016075 rRNA catabolic process IBA
 biological_processGO:0031125 rRNA 3"-end processing IBA
 biological_processGO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3"-5" IBA
 biological_processGO:0034475 U4 snRNA 3"-end processing IBA
 biological_processGO:0071028 nuclear mRNA surveillance IBA
 biological_processGO:0071051 polyadenylation-dependent snoRNA 3"-end processing IBA
 cellular_componentGO:0000176 nuclear exosome (RNase complex) IBA
 cellular_componentGO:0000177 cytoplasmic exosome (RNase complex) IBA
 cellular_componentGO:0000178 exosome (RNase complex) ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003723 RNA binding IEA


Pathways (from Reactome)
Pathway description
mRNA decay by 3 to 5 exoribonuclease
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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