ENSDARG00000103432


Danio rerio

Features
Gene ID: ENSDARG00000103432
  
Biological name :exosc4
  
Synonyms : exosc4 / exosome component 4
  
Possible biological names infered from orthology : Exosome complex component RRP41 / Q921I9 / Q9NPD3
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 1939391
Gene end: 1943113
  
Corresponding Affymetrix probe sets: Dr.9715.1.S1_at (Zebrafish Array)   Dr.9715.1.S1_a_at (Zebrafish Array)   Dr.9715.2.S1_x_at (Zebrafish Array)   Dr.9715.3.S1_a_at (Zebrafish Array)   Dr.9715.3.S1_x_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000138743
swissprot - A0A0R4IV90
ZFIN ID - ZDB-GENE-040426-1702
Ensembl - ENSDARG00000103432
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EXOSC4ENSG00000178896Homo sapiens
 Exosc4ENSMUSG00000034259Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
exosc6 / Q6P0I8 / exosome component 6 / Q5RKV6* / Q8BTW3* / Exosome complex component MTR3 *ENSDARG0000003606030


Protein motifs (from Interpro)
Interpro ID Name
 IPR001247  Exoribonuclease, phosphorolytic domain 1
 IPR015847  Exoribonuclease, phosphorolytic domain 2
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR027408  PNPase/RNase PH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
mRNA decay by 3 to 5 exoribonuclease
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000084 yolk yolk circular , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
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 ZFA:0000123 liver liver quality , abnormal
liver hypoplastic , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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