ENSDARG00000036375


Danio rerio

Features
Gene ID: ENSDARG00000036375
  
Biological name :cyfip2
  
Synonyms : cyfip2 / cytoplasmic FMR1 interacting protein 2
  
Possible biological names infered from orthology : Q5SQX6 / Q96F07
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 33982007
Gene end: 34044452
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000124883
Ensembl peptide - ENSDARP00000150209
Ensembl peptide - ENSDARP00000147949
Ensembl peptide - ENSDARP00000106311
NCBI entrez gene - 100002872     See in Manteia.
RefSeq - NM_001097587
RefSeq Peptide - NP_001091056
swissprot - B3DIT1
swissprot - A5A5E1
ZFIN ID - ZDB-GENE-080724-2
Ensembl - ENSDARG00000036375
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYFIP2ENSGALG00000003818Gallus gallus
 CYFIP2ENSG00000055163Homo sapiens
 Cyfip2ENSMUSG00000020340Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cyfip1 / cytoplasmic FMR1 interacting protein 1 / Q7L576* / Q7TMB8*ENSDARG0000004434586


Protein motifs (from Interpro)
Interpro ID Name
 IPR008081  Cytoplasmic FMR1-interacting
 IPR009828  Protein of unknown function DUF1394


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010842 retina layer formation IMP
 biological_processGO:0031290 retinal ganglion cell axon guidance IMP
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain quality , abnormal
Show

 ZFA:0000076 swim bladder swim bladder aplastic , abnormal
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 ZFA:0000252 optic tract optic tract composition , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
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 ZFA:0000435 cranial nerve II cranial nerve II composition , abnormal
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 ZFA:0000445 optic tectum optic tectum composition , abnormal
optic tectum flattened , abnormal
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 ZFA:0000655 dorsomedial optic tract dorsomedial optic tract composition , abnormal
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 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
whole organism lethal (sensu genetics) , abnormal
whole organism unbalanced , abnormal
whole organism decreased behavioural activity , abnormal
whole organism circling , abnormal
whole organism viability , abnormal
whole organism movement quality , abnormal
Show

 ZFA:0001135 neural tube neural tube quality , abnormal
Show

 ZFA:0009255 amacrine cell amacrine cell mislocalised , abnormal
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 ZFA:0009310 retinal ganglion cell retinal ganglion cell mislocalised , abnormal
retinal ganglion cell axon misrouted , abnormal
retinal ganglion cell axon irregular spatial pattern , abnormal
retinal ganglion cell axon branched , abnormal
retinal ganglion cell axon displaced , abnormal
retinal ganglion cell axon organization quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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