ENSG00000055163


Homo sapiens

Features
Gene ID: ENSG00000055163
  
Biological name :CYFIP2
  
Synonyms : CYFIP2 / cytoplasmic FMR1 interacting protein 2 / Q96F07
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q33.3
Gene start: 157266079
Gene end: 157395595
  
Corresponding Affymetrix probe sets: 215785_s_at (Human Genome U133 Plus 2.0 Array)   220999_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000428079
Ensembl peptide - ENSP00000484819
Ensembl peptide - ENSP00000482739
Ensembl peptide - ENSP00000480605
Ensembl peptide - ENSP00000479968
Ensembl peptide - ENSP00000479719
Ensembl peptide - ENSP00000479376
Ensembl peptide - ENSP00000479211
Ensembl peptide - ENSP00000478058
Ensembl peptide - ENSP00000430904
Ensembl peptide - ENSP00000403793
Ensembl peptide - ENSP00000428009
NCBI entrez gene - 26999     See in Manteia.
OMIM - 606323
RefSeq - XM_017009342
RefSeq - NM_001037333
RefSeq - NM_001291721
RefSeq - NM_001291722
RefSeq - NM_014376
RefSeq - XM_011534516
RefSeq - XM_017009341
RefSeq Peptide - NP_001032410
RefSeq Peptide - NP_001278650
RefSeq Peptide - NP_001278651
RefSeq Peptide - NP_055191
swissprot - E5RKA3
swissprot - A0A087WZL7
swissprot - A0A087WWZ1
swissprot - A0A087WVE1
swissprot - A0A087WV63
swissprot - E7EVJ5
swissprot - A0A087WTQ3
swissprot - H7C229
swissprot - Q96F07
swissprot - E7EW33
Ensembl - ENSG00000055163
  
Related genetic diseases (OMIM): 618008 - Epileptic encephalopathy, early infantile, 65, 618008
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyfip2ENSDARG00000036375Danio rerio
 CYFIP2ENSGALG00000003818Gallus gallus
 Cyfip2ENSMUSG00000020340Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYFIP1 / Q7L576 / cytoplasmic FMR1 interacting protein 1ENSG0000027374986


Protein motifs (from Interpro)
Interpro ID Name
 IPR008081  Cytoplasmic FMR1-interacting
 IPR009828  Protein of unknown function DUF1394


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0045862 positive regulation of proteolysis IDA
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway IEA
 biological_processGO:0097202 activation of cysteine-type endopeptidase activity IDA
 biological_processGO:0097484 dendrite extension IEA
 biological_processGO:0098609 cell-cell adhesion IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0045202 synapse IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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