ENSDARG00000036613


Danio rerio

Features
Gene ID: ENSDARG00000036613
  
Biological name :tab1
  
Synonyms : tab1 / TGF-beta activated kinase 1/MAP3K7 binding protein 1
  
Possible biological names infered from orthology : Q15750 / Q8CF89 / TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 181142
Gene end: 185297
  
Corresponding Affymetrix probe sets: Dr.16754.1.S1_at (Zebrafish Array)   Dr.16754.2.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000053182
swissprot - F1QKC2
ZFIN ID - ZDB-GENE-060628-1
Ensembl - ENSDARG00000036613
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TAB1ENSGALG00000012150Gallus gallus
 TAB1ENSG00000100324Homo sapiens
 Tab1ENSMUSG00000022414Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001932  PPM-type phosphatase domain
 IPR015655  Protein phosphatase 2C family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IEA


Pathways (from Reactome)
Pathway description
NOD1/2 Signaling Pathway
FCERI mediated NF-kB activation
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
activated TAK1 mediates p38 MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
TNFR1-induced NFkappaB signaling pathway
CLEC7A (Dectin-1) signaling
Ub-specific processing proteases
Interleukin-1 signaling
IRAK2 mediated activation of TAK1 complex
TRAF6-mediated induction of TAK1 complex within TLR4 complex
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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