ENSDARG00000037559


Danio rerio

Features
Gene ID: ENSDARG00000037559
  
Biological name :uba1
  
Synonyms : uba1 / ubiquitin-like modifier activating enzyme 1
  
Possible biological names infered from orthology : P22314 / P31254 / Q02053 / Uba1y / ubiquitin-activating enzyme, Chr Y
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 20640484
Gene end: 20664621
  
Corresponding Affymetrix probe sets: Dr.25294.2.S1_at (Zebrafish Array)   NM_213062_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000054690
Ensembl peptide - ENSDARP00000120542
Ensembl peptide - ENSDARP00000119427
NCBI entrez gene - 406335     See in Manteia.
RefSeq - NM_213062
RefSeq Peptide - NP_998227
swissprot - E9QFW7
swissprot - E9QEY2
swissprot - F1RCA1
ZFIN ID - ZDB-GENE-040426-2009
Ensembl - ENSDARG00000037559
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UBA1ENSG00000130985Homo sapiens
 Uba1ENSMUSG00000001924Mus musculus
 Uba1yENSMUSG00000069053Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
uba7 / ubiquitin-like modifier activating enzyme 7 / P41226*ENSDARG0000006122255
si:dkey-82j4.2 / UBA6* / A0AVT1* / Q8C7R4* / ubiquitin like modifier activating enzyme 6*ENSDARG0000008001940


Protein motifs (from Interpro)
Interpro ID Name
 IPR000011  Ubiquitin/SUMO-activating enzyme E1
 IPR000594  THIF-type NAD/FAD binding fold
 IPR018075  Ubiquitin-activating enzyme E1
 IPR018965  Ubiquitin-activating enzyme E1, C-terminal
 IPR019572  Ubiquitin-activating enzyme, catalytic cysteine domain
 IPR032418  Ubiquitin-activating enzyme E1, FCCH domain
 IPR032420  Ubiquitin-activating enzyme E1, four-helix bundle
 IPR033127  Ubiquitin-activating enzyme E1, Cys active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0006974 cellular response to DNA damage stimulus IBA
 biological_processGO:0007409 axonogenesis IMP
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004839 ubiquitin activating enzyme activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008641 ubiquitin-like modifier activating enzyme activity IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009052 motor neuron motor neuron axon branchiness , abnormal
motor neuron collateral sprouting process quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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