ENSDARG00000061222


Danio rerio

Features
Gene ID: ENSDARG00000061222
  
Biological name :uba7
  
Synonyms : uba7 / ubiquitin-like modifier activating enzyme 7
  
Possible biological names infered from orthology : P41226
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 52947186
Gene end: 53036902
  
Corresponding Affymetrix probe sets: Dr.17648.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000128383
Ensembl peptide - ENSDARP00000147332
NCBI entrez gene - 100001302     See in Manteia.
RefSeq - XM_005155876
swissprot - E7EYF3
ZFIN ID - ZDB-GENE-121120-4
Ensembl - ENSDARG00000061222
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UBA7ENSGALG00000036263Gallus gallus
 UBA7ENSG00000182179Homo sapiens
 Uba7ENSMUSG00000032596Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
uba1 / ubiquitin-like modifier activating enzyme 1 / Uba1y* / P31254* / Q02053* / P22314* / ubiquitin-activating enzyme, Chr Y*ENSDARG0000003755957
si:dkey-82j4.2 / UBA6* / A0AVT1* / Q8C7R4* / ubiquitin like modifier activating enzyme 6*ENSDARG0000008001939


Protein motifs (from Interpro)
Interpro ID Name
 IPR000011  Ubiquitin/SUMO-activating enzyme E1
 IPR000594  THIF-type NAD/FAD binding fold
 IPR018074  Ubiquitin-activating enzyme E1, conserved site
 IPR018075  Ubiquitin-activating enzyme E1
 IPR018965  Ubiquitin-activating enzyme E1, C-terminal
 IPR019572  Ubiquitin-activating enzyme, catalytic cysteine domain
 IPR032418  Ubiquitin-activating enzyme E1, FCCH domain
 IPR032420  Ubiquitin-activating enzyme E1, four-helix bundle
 IPR033127  Ubiquitin-activating enzyme E1, Cys active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0006974 cellular response to DNA damage stimulus IBA
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004839 ubiquitin activating enzyme activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008641 ubiquitin-like modifier activating enzyme activity IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000086374 isg15 / ISG15 ubiquitin-like modifier / P05161* / Q64339* / Ubiquitin-like protein ISG15 *  / complex / reaction






 

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