ENSDARG00000086374


Danio rerio

Features
Gene ID: ENSDARG00000086374
  
Biological name :isg15
  
Synonyms : isg15 / ISG15 ubiquitin-like modifier
  
Possible biological names infered from orthology : P05161 / Q64339 / Ubiquitin-like protein ISG15
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 20112032
Gene end: 20113284
  
Corresponding Affymetrix probe sets: Dr.17659.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000112153
NCBI entrez gene - 558956     See in Manteia.
RefSeq - NM_001204169
RefSeq Peptide - NP_001191098
swissprot - A2BHB8
ZFIN ID - ZDB-GENE-021211-1
Ensembl - ENSDARG00000086374
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ISG15ENSG00000187608Homo sapiens
 Isg15ENSMUSG00000035692Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:ch211-202a12.4 / UBC* / P0CG48* / P0CG50* / ubiquitin C*ENSDARG0000000236925
ubc / ubiquitin C / P0CG48* / P0CG50*ENSDARG0000010263225
ubb / ubiquitin BENSDARG0000009331325


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR019956  Ubiquitin
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
Termination of translesion DNA synthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003032 eif4a1b / eukaryotic translation initiation factor 4A1B / EIF4A1* / P60842* / P60843* / Eukaryotic initiation factor 4A-I * / eukaryotic translation initiation factor 4A1*  / reaction
 ENSDARG00000005078 eif4e3 / Q66HY7 / eukaryotic translation initiation factor 4E family member 3 / Q9DBB5* / Q8N5X7* / Eukaryotic translation initiation factor 4E type 3 *  / reaction
 ENSDARG00000038585 eif4e2 / eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 / O60573*  / complex
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / complex
 ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4*  / complex
 ENSDARG00000054155 pcna / Q9PTP1 / proliferating cell nuclear antigen / P17918* / P12004* / Pcna-ps2*  / complex
 ENSDARG00000092115 eif4a1a / eukaryotic translation initiation factor 4A1A / EIF4A1* / P60842* / P60843* / Eukaryotic initiation factor 4A-I * / eukaryotic translation initiation factor 4A1*  / reaction
 ENSDARG00000088072 usp43b / ubiquitin specific peptidase 43b / USP43* / Q70EL4* / Q8BUM9* / ubiquitin specific peptidase 43*  / reaction / complex
 ENSDARG00000086374 isg15 / ISG15 ubiquitin-like modifier / P05161* / Q64339* / Ubiquitin-like protein ISG15 *  / complex
 ENSDARG00000003616 arih1 / Q6PFJ9 / ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) / Q9Z1K5* / Q9Y4X5* / E3 ubiquitin-protein ligase ARIH1 * / ariadne RBR E3 ubiquitin protein ligase 1*  / complex
 ENSDARG00000061222 uba7 / ubiquitin-like modifier activating enzyme 7 / P41226*  / complex / reaction
 ENSDARG00000036870 arih1l / Q6NW85 / ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like / ARIH1* / Q9Z1K5* / Q9Y4X5* / E3 ubiquitin-protein ligase ARIH1 * / ariadne RBR E3 ubiquitin prot...  / complex
 ENSDARG00000016477 eif4a2 / eukaryotic translation initiation factor 4A, isoform 2 / P10630* / Q14240* / eukaryotic translation initiation factor 4A2* / Mus musculus eukaryotic translation initiation factor 4...  / reaction
 ENSDARG00000099843 nedd4a / neural precursor cell expressed, developmentally down-regulated 4a / NEDD4* / P46934* / P46935* / neural precursor cell expressed, developmentally down-regulated 4* / neural precur...  / complex / reaction
 ENSDARG00000015835 eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 related sequence 1  / complex
 ENSDARG00000103494 usp43a / ubiquitin specific peptidase 43a / USP43* / Q70EL4* / Q8BUM9* / ubiquitin specific peptidase 43*  / reaction / complex
 ENSDARG00000077215 eif4g3a / eukaryotic translation initiation factor 4 gamma, 3a / O43432* / EIF4G3* / eukaryotic translation initiation factor 4 gamma 3* / Mus musculus eukaryotic translation initiation fac...  / reaction






 

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