ENSDARG00000077215


Danio rerio

Features
Gene ID: ENSDARG00000077215
  
Biological name :eif4g3a
  
Synonyms : eif4g3a / eukaryotic translation initiation factor 4 gamma, 3a
  
Possible biological names infered from orthology : EIF4G3 / eukaryotic translation initiation factor 4 gamma 3 / Mus musculus eukaryotic translation initiation factor 4 gamma, 3 (Eif4g3), transcript variant 4, mRNA. / O43432
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 27828212
Gene end: 27917730
  
Corresponding Affymetrix probe sets: Dr.14976.1.S1_at (Zebrafish Array)   Dr.16991.1.A1_at (Zebrafish Array)   Dr.16991.2.A1_at (Zebrafish Array)   XM_689398_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000146015
Ensembl peptide - ENSDARP00000156160
Ensembl peptide - ENSDARP00000152880
Ensembl peptide - ENSDARP00000142418
Ensembl peptide - ENSDARP00000142511
NCBI entrez gene - 566131     See in Manteia.
RefSeq - XM_009306089
RefSeq - XM_009306090
RefSeq - XM_689398
swissprot - A0A140LGY2
swissprot - A0A140LGN9
ZFIN ID - ZDB-GENE-120810-2
Ensembl - ENSDARG00000077215
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EIF4G3ENSGALG00000010084Gallus gallus
 EIF4G3ENSG00000075151Homo sapiens
 Eif4g3ENSMUSG00000028760Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eif4g3b / eukaryotic translation initiation factor 4 gamma, 3b / O43432* / EIF4G3* / eukaryotic translation initiation factor 4 gamma 3* / Mus musculus eukaryotic translation initiation fac...ENSDARG0000007433162
eif4g1a / eukaryotic translation initiation factor 4 gamma, 1a / Q6NZJ6* / EIF4G1* / Q04637* / eukaryotic translation initiation factor 4 gamma 1*ENSDARG0000000620040
eif4g2b / eukaryotic translation initiation factor 4, gamma 2b / P78344* / EIF4G2* / eukaryotic translation initiation factor 4 gamma 2* / eukaryotic translation initiation factor 4 gamma 2...ENSDARG0000005716714
eif4g2a / eukaryotic translation initiation factor 4, gamma 2a / EIF4G2* / P78344* / eukaryotic translation initiation factor 4 gamma 2*ENSDARG0000002037714
CABZ01061894.1 / EIF4G1* / Q04637* / eukaryotic translation initiation factor 4 gamma 1*ENSDARG0000011671213


Protein motifs (from Interpro)
Interpro ID Name
 IPR003307  W2 domain
 IPR003890  MIF4G-like, type 3
 IPR003891  Initiation factor eIF-4 gamma, MA3
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006413 translational initiation IEA
 molecular_functionGO:0000339 RNA cap binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003032 eif4a1b / eukaryotic translation initiation factor 4A1B / EIF4A1* / P60842* / P60843* / Eukaryotic initiation factor 4A-I * / eukaryotic translation initiation factor 4A1*  / complex
 ENSDARG00000005078 eif4e3 / Q66HY7 / eukaryotic translation initiation factor 4E family member 3 / Q9DBB5* / Q8N5X7* / Eukaryotic translation initiation factor 4E type 3 *  / complex
 ENSDARG00000092115 eif4a1a / eukaryotic translation initiation factor 4A1A / EIF4A1* / P60842* / P60843* / Eukaryotic initiation factor 4A-I * / eukaryotic translation initiation factor 4A1*  / complex
 ENSDARG00000016477 eif4a2 / eukaryotic translation initiation factor 4A, isoform 2 / P10630* / Q14240* / eukaryotic translation initiation factor 4A2* / Mus musculus eukaryotic translation initiation factor 4...  / complex
 ENSDARG00000086374 isg15 / ISG15 ubiquitin-like modifier / P05161* / Q64339* / Ubiquitin-like protein ISG15 *  / reaction
 ENSDARG00000015835 eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 related sequence 1  / reaction
 ENSDARG00000036870 arih1l / Q6NW85 / ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like / ARIH1* / Q9Z1K5* / Q9Y4X5* / E3 ubiquitin-protein ligase ARIH1 * / ariadne RBR E3 ubiquitin prot...  / reaction
 ENSDARG00000038585 eif4e2 / eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 / O60573*  / reaction
 ENSDARG00000003616 arih1 / Q6PFJ9 / ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) / Q9Z1K5* / Q9Y4X5* / E3 ubiquitin-protein ligase ARIH1 * / ariadne RBR E3 ubiquitin protein ligase 1*  / reaction






 

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