ENSDARG00000006200


Danio rerio

Features
Gene ID: ENSDARG00000006200
  
Biological name :eif4g1a
  
Synonyms : eif4g1a / eukaryotic translation initiation factor 4 gamma, 1a
  
Possible biological names infered from orthology : EIF4G1 / eukaryotic translation initiation factor 4 gamma 1 / Q04637 / Q6NZJ6
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 16798652
Gene end: 16842699
  
Corresponding Affymetrix probe sets: Dr.26512.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000151919
Ensembl peptide - ENSDARP00000154349
Ensembl peptide - ENSDARP00000081541
Ensembl peptide - ENSDARP00000081554
Ensembl peptide - ENSDARP00000114122
Ensembl peptide - ENSDARP00000147911
swissprot - B8JL45
swissprot - B8JL46
swissprot - F1R101
ZFIN ID - ZDB-GENE-070112-702
Ensembl - ENSDARG00000006200
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EIF4G1ENSGALG00000008520Gallus gallus
 EIF4G1ENSG00000114867Homo sapiens
 Eif4g1ENSMUSG00000045983Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eif4g3b / eukaryotic translation initiation factor 4 gamma, 3b / O43432* / EIF4G3* / eukaryotic translation initiation factor 4 gamma 3* / Mus musculus eukaryotic translation initiation fac...ENSDARG0000007433144
eif4g3a / eukaryotic translation initiation factor 4 gamma, 3a / O43432* / EIF4G3* / eukaryotic translation initiation factor 4 gamma 3* / Mus musculus eukaryotic translation initiation fac...ENSDARG0000007721543
CABZ01061894.1 / EIF4G1* / Q04637* / eukaryotic translation initiation factor 4 gamma 1*ENSDARG0000011671217
eif4g2a / eukaryotic translation initiation factor 4, gamma 2a / EIF4G2* / P78344* / eukaryotic translation initiation factor 4 gamma 2*ENSDARG0000002037715
eif4g2b / eukaryotic translation initiation factor 4, gamma 2b / P78344* / EIF4G2* / eukaryotic translation initiation factor 4 gamma 2* / eukaryotic translation initiation factor 4 gamma 2...ENSDARG0000005716715


Protein motifs (from Interpro)
Interpro ID Name
 IPR003307  W2 domain
 IPR003890  MIF4G-like, type 3
 IPR003891  Initiation factor eIF-4 gamma, MA3
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006413 translational initiation IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
L13a-mediated translational silencing of Ceruloplasmin expression
mTORC1-mediated signalling
Deadenylation of mRNA
AUF1 (hnRNP D0) binds and destabilizes mRNA
Translation initiation complex formation
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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