ENSDARG00000003616


Danio rerio

Features
Gene ID: ENSDARG00000003616
  
Biological name :arih1
  
Synonyms : ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) / arih1 / Q6PFJ9
  
Possible biological names infered from orthology : ariadne RBR E3 ubiquitin protein ligase 1 / E3 ubiquitin-protein ligase ARIH1 / Q9Y4X5 / Q9Z1K5
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 18879733
Gene end: 18901017
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000006476
NCBI entrez gene - 327005     See in Manteia.
RefSeq - NM_199758
RefSeq Peptide - NP_956052
swissprot - B2GS68
swissprot - Q6PFJ9
ZFIN ID - ZDB-GENE-030131-5213
Ensembl - ENSDARG00000003616
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARIH1ENSGALG00000001901Gallus gallus
 ARIH1ENSG00000166233Homo sapiens
 Arih1ENSMUSG00000025234Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
arih1l / Q6NW85 / ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like / ARIH1* / Q9Z1K5* / Q9Y4X5* / E3 ubiquitin-protein ligase ARIH1 * / ariadne RBR E3 ubiquitin prot...ENSDARG0000003687095
arih2 / ariadne homolog 2 (Drosophila) / O95376* / Q9Z1K6* / ariadne RBR E3 ubiquitin protein ligase 2* / Mus musculus ariadne RBR E3 ubiquitin protein ligase 2 (Arih2), transcript variant 2, mRNA.*ENSDARG0000001284830
ankib1b / ankyrin repeat and IBR domain containing 1b / ANKIB1* / Q6ZPS6* / Q9P2G1* / ankyrin repeat and IBR domain containing 1* / Ankyrin repeat and IBR domain-containing protein 1 *ENSDARG0000007682928
Q1L8G6 / ankib1a / ankyrin repeat and IBR domain containing 1a / ANKIB1* / Q6ZPS6* / Q9P2G1* / ankyrin repeat and IBR domain containing 1* / Ankyrin repeat and IBR domain-containing protein 1 *ENSDARG0000006076828


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR002867  IBR domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR031127  E3 ubiquitin ligase RBR family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0016567 protein ubiquitination ISS
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
 cellular_componentGO:0000151 ubiquitin ligase complex IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0016604 nuclear body ISS
 cellular_componentGO:0019005 SCF ubiquitin ligase complex ISS
 cellular_componentGO:0031462 Cul2-RING ubiquitin ligase complex ISS
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex ISS
 cellular_componentGO:0031464 Cul4A-RING E3 ubiquitin ligase complex ISS
 cellular_componentGO:0097413 Lewy body ISS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISS
 molecular_functionGO:0008270 zinc ion binding ISS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003032 eif4a1b / eukaryotic translation initiation factor 4A1B / EIF4A1* / P60842* / P60843* / Eukaryotic initiation factor 4A-I * / eukaryotic translation initiation factor 4A1*  / reaction
 ENSDARG00000005078 eif4e3 / Q66HY7 / eukaryotic translation initiation factor 4E family member 3 / Q9DBB5* / Q8N5X7* / Eukaryotic translation initiation factor 4E type 3 *  / reaction
 ENSDARG00000038585 eif4e2 / eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 / O60573*  / complex
 ENSDARG00000092115 eif4a1a / eukaryotic translation initiation factor 4A1A / EIF4A1* / P60842* / P60843* / Eukaryotic initiation factor 4A-I * / eukaryotic translation initiation factor 4A1*  / reaction
 ENSDARG00000086374 isg15 / ISG15 ubiquitin-like modifier / P05161* / Q64339* / Ubiquitin-like protein ISG15 *  / complex
 ENSDARG00000016477 eif4a2 / eukaryotic translation initiation factor 4A, isoform 2 / P10630* / Q14240* / eukaryotic translation initiation factor 4A2* / Mus musculus eukaryotic translation initiation factor 4...  / reaction
 ENSDARG00000015835 eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 related sequence 1  / complex
 ENSDARG00000077215 eif4g3a / eukaryotic translation initiation factor 4 gamma, 3a / O43432* / EIF4G3* / eukaryotic translation initiation factor 4 gamma 3* / Mus musculus eukaryotic translation initiation fac...  / reaction






 

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