ENSDARG00000038585


Danio rerio

Features
Gene ID: ENSDARG00000038585
  
Biological name :eif4e2
  
Synonyms : eif4e2 / eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2
  
Possible biological names infered from orthology : Mus musculus eukaryotic translation initiation factor 4E member 2 (Eif4e2), transcript variant 4, mRNA. / O60573 / Q8BMB3
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 45116819
Gene end: 45135618
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000020911
Ensembl peptide - ENSDARP00000107220
NCBI entrez gene - 541523     See in Manteia.
RefSeq - XM_021480199
RefSeq - NM_001014815
RefSeq Peptide - NP_001014815
swissprot - Q6PBU4
swissprot - A1L200
ZFIN ID - ZDB-GENE-040426-1728
ZFIN ID - ZDB-GENE-050327-59
Ensembl - ENSDARG00000038585
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EIF4E2ENSGALG00000007919Gallus gallus
 EIF4E2ENSG00000135930Homo sapiens
 Eif4e2ENSMUSG00000026254Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 related sequence 1ENSDARG0000001583569
eif4e1c / eukaryotic translation initiation factor 4E family member 1cENSDARG0000001227429
eif4ea / eukaryotic translation initiation factor 4ea / EIF4E* / P63073* / P06730* / eukaryotic translation initiation factor 4E*ENSDARG0000007701227
eif4eb / eukaryotic translation initiation factor 4eb / EIF4E* / P63073* / P06730* / eukaryotic translation initiation factor 4E*ENSDARG0000001327427
Q9PW28 / eif4e1b / eukaryotic translation initiation factor 4E family member 1B / A6NMX2*ENSDARG0000001456525
eif4e3 / Q66HY7 / eukaryotic translation initiation factor 4E family member 3 / Q9DBB5* / Q8N5X7* / Eukaryotic translation initiation factor 4E type 3 *ENSDARG0000000507823


Protein motifs (from Interpro)
Interpro ID Name
 IPR001040  Translation Initiation factor eIF- 4e
 IPR019770  Eukaryotic translation initiation factor 4E (eIF-4E), conserved site
 IPR023398  Translation Initiation factor eIF- 4e-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003032 eif4a1b / eukaryotic translation initiation factor 4A1B / EIF4A1* / P60842* / P60843* / Eukaryotic initiation factor 4A-I * / eukaryotic translation initiation factor 4A1*  / reaction
 ENSDARG00000005078 eif4e3 / Q66HY7 / eukaryotic translation initiation factor 4E family member 3 / Q9DBB5* / Q8N5X7* / Eukaryotic translation initiation factor 4E type 3 *  / reaction
 ENSDARG00000036870 arih1l / Q6NW85 / ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like / ARIH1* / Q9Z1K5* / Q9Y4X5* / E3 ubiquitin-protein ligase ARIH1 * / ariadne RBR E3 ubiquitin prot...  / complex
 ENSDARG00000086374 isg15 / ISG15 ubiquitin-like modifier / P05161* / Q64339* / Ubiquitin-like protein ISG15 *  / complex
 ENSDARG00000003616 arih1 / Q6PFJ9 / ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) / Q9Z1K5* / Q9Y4X5* / E3 ubiquitin-protein ligase ARIH1 * / ariadne RBR E3 ubiquitin protein ligase 1*  / complex
 ENSDARG00000092115 eif4a1a / eukaryotic translation initiation factor 4A1A / EIF4A1* / P60842* / P60843* / Eukaryotic initiation factor 4A-I * / eukaryotic translation initiation factor 4A1*  / reaction
 ENSDARG00000016477 eif4a2 / eukaryotic translation initiation factor 4A, isoform 2 / P10630* / Q14240* / eukaryotic translation initiation factor 4A2* / Mus musculus eukaryotic translation initiation factor 4...  / reaction
 ENSDARG00000077215 eif4g3a / eukaryotic translation initiation factor 4 gamma, 3a / O43432* / EIF4G3* / eukaryotic translation initiation factor 4 gamma 3* / Mus musculus eukaryotic translation initiation fac...  / reaction






 

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