ENSDARG00000077012


Danio rerio

Features
Gene ID: ENSDARG00000077012
  
Biological name :eif4ea
  
Synonyms : eif4ea / eukaryotic translation initiation factor 4ea
  
Possible biological names infered from orthology : EIF4E / eukaryotic translation initiation factor 4E / P06730 / P63073
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 43577164
Gene end: 43586150
  
Corresponding Affymetrix probe sets: Dr.5294.1.S1_at (Zebrafish Array)   NM_131733_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000103599
NCBI entrez gene - 79380     See in Manteia.
RefSeq - NM_131733
RefSeq Peptide - NP_571808
swissprot - F1Q900
ZFIN ID - ZDB-GENE-040413-1
Ensembl - ENSDARG00000077012
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EIF4EENSGALG00000042112Gallus gallus
 EIF4EENSG00000151247Homo sapiens
 Eif4eENSMUSG00000028156Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eif4eb / eukaryotic translation initiation factor 4eb / EIF4E* / P63073* / P06730* / eukaryotic translation initiation factor 4E*ENSDARG0000001327487
eif4e1c / eukaryotic translation initiation factor 4E family member 1cENSDARG0000001227469
Q9PW28 / eif4e1b / eukaryotic translation initiation factor 4E family member 1B / A6NMX2*ENSDARG0000001456563
eif4e2 / eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 / O60573*ENSDARG0000003858530
eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 related sequence 1ENSDARG0000001583528
eif4e3 / Q66HY7 / eukaryotic translation initiation factor 4E family member 3 / Q9DBB5* / Q8N5X7* / Eukaryotic translation initiation factor 4E type 3 *ENSDARG0000000507826


Protein motifs (from Interpro)
Interpro ID Name
 IPR001040  Translation Initiation factor eIF- 4e
 IPR019770  Eukaryotic translation initiation factor 4E (eIF-4E), conserved site
 IPR023398  Translation Initiation factor eIF- 4e-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
L13a-mediated translational silencing of Ceruloplasmin expression
mTORC1-mediated signalling
Deadenylation of mRNA
Translation initiation complex formation
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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