ENSDARG00000005078


Danio rerio

Features
Gene ID: ENSDARG00000005078
  
Biological name :eif4e3
  
Synonyms : eif4e3 / eukaryotic translation initiation factor 4E family member 3 / Q66HY7
  
Possible biological names infered from orthology : Eukaryotic translation initiation factor 4E type 3 / Q8N5X7 / Q9DBB5
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 10724042
Gene end: 10745319
  
Corresponding Affymetrix probe sets: Dr.1710.1.A1_at (Zebrafish Array)   Dr.1710.2.S1_at (Zebrafish Array)   NM_001004589_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000015325
Ensembl peptide - ENSDARP00000123404
NCBI entrez gene - 447850     See in Manteia.
RefSeq - NM_001004589
RefSeq Peptide - NP_001004589
swissprot - E9QC27
swissprot - E2IQH2
swissprot - Q66HY7
ZFIN ID - ZDB-GENE-040912-156
Ensembl - ENSDARG00000005078
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EIF4E3ENSGALG00000007780Gallus gallus
 EIF4E3ENSG00000163412Homo sapiens
 Eif4e3ENSMUSG00000093661Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eif4eb / eukaryotic translation initiation factor 4eb / EIF4E* / P63073* / P06730* / eukaryotic translation initiation factor 4E*ENSDARG0000001327426
eif4ea / eukaryotic translation initiation factor 4ea / EIF4E* / P63073* / P06730* / eukaryotic translation initiation factor 4E*ENSDARG0000007701225
eif4e2 / eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 / O60573*ENSDARG0000003858524
eif4e1c / eukaryotic translation initiation factor 4E family member 1cENSDARG0000001227424
Q9PW28 / eif4e1b / eukaryotic translation initiation factor 4E family member 1B / A6NMX2*ENSDARG0000001456523
eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 related sequence 1ENSDARG0000001583523


Protein motifs (from Interpro)
Interpro ID Name
 IPR001040  Translation Initiation factor eIF- 4e
 IPR023398  Translation Initiation factor eIF- 4e-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0006417 regulation of translation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005845 mRNA cap binding complex ISS
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003032 eif4a1b / eukaryotic translation initiation factor 4A1B / EIF4A1* / P60842* / P60843* / Eukaryotic initiation factor 4A-I * / eukaryotic translation initiation factor 4A1*  / complex
 ENSDARG00000077215 eif4g3a / eukaryotic translation initiation factor 4 gamma, 3a / O43432* / EIF4G3* / eukaryotic translation initiation factor 4 gamma 3* / Mus musculus eukaryotic translation initiation fac...  / complex
 ENSDARG00000038585 eif4e2 / eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 / O60573*  / reaction
 ENSDARG00000003616 arih1 / Q6PFJ9 / ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) / Q9Z1K5* / Q9Y4X5* / E3 ubiquitin-protein ligase ARIH1 * / ariadne RBR E3 ubiquitin protein ligase 1*  / reaction
 ENSDARG00000036870 arih1l / Q6NW85 / ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like / ARIH1* / Q9Z1K5* / Q9Y4X5* / E3 ubiquitin-protein ligase ARIH1 * / ariadne RBR E3 ubiquitin prot...  / reaction
 ENSDARG00000086374 isg15 / ISG15 ubiquitin-like modifier / P05161* / Q64339* / Ubiquitin-like protein ISG15 *  / reaction
 ENSDARG00000015835 eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 related sequence 1  / reaction
 ENSDARG00000092115 eif4a1a / eukaryotic translation initiation factor 4A1A / EIF4A1* / P60842* / P60843* / Eukaryotic initiation factor 4A-I * / eukaryotic translation initiation factor 4A1*  / complex
 ENSDARG00000016477 eif4a2 / eukaryotic translation initiation factor 4A, isoform 2 / P10630* / Q14240* / eukaryotic translation initiation factor 4A2* / Mus musculus eukaryotic translation initiation factor 4...  / complex






 

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