ENSDARG00000036870


Danio rerio

Features
Gene ID: ENSDARG00000036870
  
Biological name :arih1l
  
Synonyms : ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like / arih1l / Q6NW85
  
Possible biological names infered from orthology : ariadne RBR E3 ubiquitin protein ligase 1 / ARIH1 / E3 ubiquitin-protein ligase ARIH1 / Q9Y4X5 / Q9Z1K5
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 13491452
Gene end: 13514737
  
Corresponding Affymetrix probe sets: Dr.15627.1.A1_at (Zebrafish Array)   Dr.15627.2.S1_at (Zebrafish Array)   Dr.21388.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000053534
NCBI entrez gene - 405859     See in Manteia.
swissprot - Q6NW85
ZFIN ID - ZDB-GENE-040426-2395
Ensembl - ENSDARG00000036870
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARIH1ENSGALG00000001901Gallus gallus
 ARIH1ENSG00000166233Homo sapiens
 Arih1ENSMUSG00000025234Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
arih1 / Q6PFJ9 / ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) / Q9Z1K5* / Q9Y4X5* / E3 ubiquitin-protein ligase ARIH1 * / ariadne RBR E3 ubiquitin protein ligase 1*ENSDARG0000000361694
arih2 / ariadne homolog 2 (Drosophila) / O95376* / Q9Z1K6* / ariadne RBR E3 ubiquitin protein ligase 2* / Mus musculus ariadne RBR E3 ubiquitin protein ligase 2 (Arih2), transcript variant 2, mRNA.*ENSDARG0000001284830
ankib1b / ankyrin repeat and IBR domain containing 1b / ANKIB1* / Q6ZPS6* / Q9P2G1* / ankyrin repeat and IBR domain containing 1* / Ankyrin repeat and IBR domain-containing protein 1 *ENSDARG0000007682927
Q1L8G6 / ankib1a / ankyrin repeat and IBR domain containing 1a / ANKIB1* / Q6ZPS6* / Q9P2G1* / ankyrin repeat and IBR domain containing 1* / Ankyrin repeat and IBR domain-containing protein 1 *ENSDARG0000006076827


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR002867  IBR domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0016567 protein ubiquitination ISS
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
 cellular_componentGO:0000151 ubiquitin ligase complex IBA
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISS
 molecular_functionGO:0008270 zinc ion binding ISS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003032 eif4a1b / eukaryotic translation initiation factor 4A1B / EIF4A1* / P60842* / P60843* / Eukaryotic initiation factor 4A-I * / eukaryotic translation initiation factor 4A1*  / reaction
 ENSDARG00000005078 eif4e3 / Q66HY7 / eukaryotic translation initiation factor 4E family member 3 / Q9DBB5* / Q8N5X7* / Eukaryotic translation initiation factor 4E type 3 *  / reaction
 ENSDARG00000038585 eif4e2 / eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 / O60573*  / complex
 ENSDARG00000092115 eif4a1a / eukaryotic translation initiation factor 4A1A / EIF4A1* / P60842* / P60843* / Eukaryotic initiation factor 4A-I * / eukaryotic translation initiation factor 4A1*  / reaction
 ENSDARG00000086374 isg15 / ISG15 ubiquitin-like modifier / P05161* / Q64339* / Ubiquitin-like protein ISG15 *  / complex
 ENSDARG00000016477 eif4a2 / eukaryotic translation initiation factor 4A, isoform 2 / P10630* / Q14240* / eukaryotic translation initiation factor 4A2* / Mus musculus eukaryotic translation initiation factor 4...  / reaction
 ENSDARG00000015835 eif4e2rs1 / eukaryotic translation initiation factor 4E family member 2 related sequence 1  / complex
 ENSDARG00000077215 eif4g3a / eukaryotic translation initiation factor 4 gamma, 3a / O43432* / EIF4G3* / eukaryotic translation initiation factor 4 gamma 3* / Mus musculus eukaryotic translation initiation fac...  / reaction






 

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