ENSDARG00000038428


Danio rerio

Features
Gene ID: ENSDARG00000038428
  
Biological name :sulf1
  
Synonyms : sulf1 / sulfatase 1
  
Possible biological names infered from orthology : Extracellular sulfatase Sulf-1 / Q8IWU6 / Q8K007
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 19414561
Gene end: 19588659
  
Corresponding Affymetrix probe sets: Dr.9711.1.A1_at (Zebrafish Array)   DrAffx.2.61.S1_at (Zebrafish Array)   NM_001003846_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000156692
Ensembl peptide - ENSDARP00000013515
Ensembl peptide - ENSDARP00000056079
Ensembl peptide - ENSDARP00000056080
Ensembl peptide - ENSDARP00000114700
Ensembl peptide - ENSDARP00000117345
Ensembl peptide - ENSDARP00000121874
Ensembl peptide - ENSDARP00000153504
Ensembl peptide - ENSDARP00000153732
Ensembl peptide - ENSDARP00000154297
Ensembl peptide - ENSDARP00000154873
NCBI entrez gene - 337298     See in Manteia.
RefSeq - NM_001003846
RefSeq Peptide - NP_001003846
swissprot - Q6EFA0
swissprot - Q6EFA1
swissprot - Q6EF99
swissprot - F1R7B9
ZFIN ID - ZDB-GENE-030131-9242
Ensembl - ENSDARG00000038428
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SULF1ENSGALG00000039553Gallus gallus
 SULF1ENSG00000137573Homo sapiens
 Sulf1ENSMUSG00000016918Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sulf2b / sulfatase 2b / SULF2* / Q8IWU5* / Q8CFG0* / sulfatase 2* / Mus musculus sulfatase 2 (Sulf2), transcript variant 4, mRNA.*ENSDARG0000001383849
sulf2a / sulfatase 2aENSDARG0000001842346
gnsa / glucosamine (N-acetyl)-6-sulfatase a / GNS* / P15586* / Q8BFR4* / glucosamine (N-acetyl)-6-sulfatase*ENSDARG0000002376620
gnsb / glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), bENSDARG0000009829620


Protein motifs (from Interpro)
Interpro ID Name
 IPR000917  Sulfatase, N-terminal
 IPR014615  Extracellular sulfatase
 IPR017849  Alkaline phosphatase-like, alpha/beta/alpha
 IPR017850  Alkaline-phosphatase-like, core domain superfamily
 IPR024607  Sulfatase, conserved site
 IPR024609  Extracellular sulfatase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001570 vasculogenesis IMP
 biological_processGO:0001756 somitogenesis IMP
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0008015 blood circulation IMP
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning IMP
 biological_processGO:0048070 regulation of developmental pigmentation IMP
 biological_processGO:0048885 neuromast deposition IMP
 biological_processGO:2000290 regulation of myotome development IMP
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0009986 cell surface IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008484 sulfuric ester hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood accumulation caudal vein plexus , abnormal
Show

 ZFA:0000011 caudal artery caudal artery immature , abnormal
caudal artery morphology , abnormal
Show

 ZFA:0000014 dorsal aorta dorsal aorta blood circulation disrupted , abnormal
Show

 ZFA:0000029 hindbrain hindbrain edematous , abnormal
Show

 ZFA:0000075 spinal cord spinal cord has fewer parts of type oligodendrocyte , abnormal
spinal cord has fewer parts of type spinal cord interneuron , abnormal
spinal cord has fewer parts of type Kolmer-Agduhr neuron , abnormal
spinal cord ventral region poorly differentiated , abnormal
spinal cord smoothened signaling pathway decreased process quality , abnormal
spinal cord curved , abnormal
Show

 ZFA:0000155 somite somite shape , abnormal
somite decreased width , abnormal
somite obtuse angle to somite , abnormal
somite tight , abnormal
somite has fewer parts of type muscle pioneer , abnormal
somite has fewer parts of type fast muscle cell , abnormal
Show

 ZFA:0000243 neuromast neuromast decreased size , abnormal
neuromast dispersed , abnormal
neuromast decreased amount , abnormal
Show

 ZFA:0000671 horizontal myoseptum horizontal myoseptum absent , abnormal
Show

 ZFA:0001058 caudal fin caudal fin curved , abnormal
caudal fin increased width , abnormal
Show

 ZFA:0001073 axial vasculature axial vasculature blood circulation disrupted , abnormal
Show

 ZFA:0001086 muscle pioneer muscle pioneer decreased amount , abnormal
Show

 ZFA:0001114 head head hemorrhagic , abnormal
Show

 ZFA:0001135 neural tube neural tube smoothened signaling pathway decreased process quality , abnormal
Show

 ZFA:0001267 cranial vasculature cranial vasculature blood circulation disrupted , abnormal
cranial vasculature lacks parts or has fewer parts of type central artery , abnormal
cranial vasculature broken , abnormal
Show

 ZFA:0001286 caudal vein plexus caudal vein plexus disorganized , abnormal
Show

 ZFA:0001469 lateral line lateral line morphology , abnormal
Show

 ZFA:0005020 central artery central artery immature , abnormal
central artery blood vessel lumenization disrupted , abnormal
Show

 ZFA:0005037 post-vent vasculature post-vent vasculature blood circulation disrupted , abnormal
Show

 ZFA:0005223 lateral larval melanophore stripe lateral larval melanophore stripe absent , abnormal
lateral larval melanophore stripe has fewer parts of type melanocyte , abnormal
Show

 ZFA:0009114 muscle cell muscle cell sparse , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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