ENSDARG00000023766


Danio rerio

Features
Gene ID: ENSDARG00000023766
  
Biological name :gnsa
  
Synonyms : glucosamine (N-acetyl)-6-sulfatase a / gnsa
  
Possible biological names infered from orthology : glucosamine (N-acetyl)-6-sulfatase / GNS / P15586 / Q8BFR4
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 4509996
Gene end: 4524284
  
Corresponding Affymetrix probe sets: Dr.14866.1.A1_at (Zebrafish Array)   NM_001030208_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000031210
NCBI entrez gene - 566506     See in Manteia.
RefSeq - NM_001030208
RefSeq Peptide - NP_001025379
swissprot - F1R152
ZFIN ID - ZDB-GENE-050107-5
Ensembl - ENSDARG00000023766
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GNSENSGALG00000009856Gallus gallus
 GNSENSG00000135677Homo sapiens
 GnsENSMUSG00000034707Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gnsb / glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), bENSDARG0000009829656
sulf2b / sulfatase 2b / SULF2* / Q8IWU5* / Q8CFG0* / sulfatase 2* / Mus musculus sulfatase 2 (Sulf2), transcript variant 4, mRNA.*ENSDARG0000001383840
sulf2a / sulfatase 2aENSDARG0000001842340
sulf1 / sulfatase 1 / Q8IWU6* / Q8K007* / Extracellular sulfatase Sulf-1 *ENSDARG0000003842839


Protein motifs (from Interpro)
Interpro ID Name
 IPR000917  Sulfatase, N-terminal
 IPR012251  N-acetylglucosamine-6-sulfatase
 IPR015981  N-acetylglucosamine-6-sulfatase, metazoan
 IPR017849  Alkaline phosphatase-like, alpha/beta/alpha
 IPR017850  Alkaline-phosphatase-like, core domain superfamily
 IPR024607  Sulfatase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0030203 glycosaminoglycan metabolic process IEA
 cellular_componentGO:0005764 lysosome IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0008449 N-acetylglucosamine-6-sulfatase activity IEA
 molecular_functionGO:0008484 sulfuric ester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Keratan sulfate degradation
Lysosome Vesicle Biogenesis
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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