ENSG00000137573


Homo sapiens

Features
Gene ID: ENSG00000137573
  
Biological name :SULF1
  
Synonyms : Q8IWU6 / SULF1 / sulfatase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q13.2
Gene start: 69466624
Gene end: 69660915
  
Corresponding Affymetrix probe sets: 212344_at (Human Genome U133 Plus 2.0 Array)   212353_at (Human Genome U133 Plus 2.0 Array)   212354_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000390315
Ensembl peptide - ENSP00000480454
Ensembl peptide - ENSP00000436949
Ensembl peptide - ENSP00000436608
Ensembl peptide - ENSP00000434128
Ensembl peptide - ENSP00000432178
Ensembl peptide - ENSP00000431753
Ensembl peptide - ENSP00000431308
Ensembl peptide - ENSP00000403040
Ensembl peptide - ENSP00000260128
Ensembl peptide - ENSP00000385704
NCBI entrez gene - 23213     See in Manteia.
OMIM - 610012
RefSeq - XM_017013250
RefSeq - XM_011517495
RefSeq - XM_011517494
RefSeq - XM_006716442
RefSeq - XM_006716441
RefSeq - XM_006716440
RefSeq - XM_006716439
RefSeq - NM_001128204
RefSeq - NM_001128205
RefSeq - NM_001128206
RefSeq - XM_006716438
RefSeq - NM_015170
RefSeq Peptide - NP_001121676
RefSeq Peptide - NP_001121677
RefSeq Peptide - NP_001121678
RefSeq Peptide - NP_055985
swissprot - Q8IWU6
swissprot - E9PS14
swissprot - H0YDR1
swissprot - A0A024R809
swissprot - A0A087WWR8
swissprot - E9PI06
swissprot - E9PJL8
swissprot - E9PLS5
swissprot - E9PPQ3
Ensembl - ENSG00000137573
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sulf1ENSDARG00000038428Danio rerio
 SULF1ENSGALG00000039553Gallus gallus
 Sulf1ENSMUSG00000016918Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SULF2 / Q8IWU5 / sulfatase 2ENSG0000019656265
GNS / P15586 / glucosamine (N-acetyl)-6-sulfataseENSG0000013567725


Protein motifs (from Interpro)
Interpro ID Name
 IPR000917  Sulfatase, N-terminal
 IPR014615  Extracellular sulfatase
 IPR017849  Alkaline phosphatase-like, alpha/beta/alpha
 IPR017850  Alkaline-phosphatase-like, core domain superfamily
 IPR024607  Sulfatase, conserved site
 IPR024609  Extracellular sulfatase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development ISS
 biological_processGO:0001937 negative regulation of endothelial cell proliferation IDA
 biological_processGO:0002063 chondrocyte development ISS
 biological_processGO:0003094 glomerular filtration ISS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production ISS
 biological_processGO:0014846 esophagus smooth muscle contraction ISS
 biological_processGO:0016525 negative regulation of angiogenesis IDA
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IDA
 biological_processGO:0030201 heparan sulfate proteoglycan metabolic process NAS
 biological_processGO:0030336 negative regulation of cell migration IMP
 biological_processGO:0030513 positive regulation of BMP signaling pathway IMP
 biological_processGO:0032836 glomerular basement membrane development ISS
 biological_processGO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway ISS
 biological_processGO:0040036 regulation of fibroblast growth factor receptor signaling pathway IMP
 biological_processGO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway IMP
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway IDA
 biological_processGO:0048706 embryonic skeletal system development ISS
 biological_processGO:0051216 cartilage development ISS
 biological_processGO:0060348 bone development ISS
 biological_processGO:0060384 innervation ISS
 biological_processGO:0060686 negative regulation of prostatic bud formation ISS
 cellular_componentGO:0005615 extracellular space NAS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus ISS
 cellular_componentGO:0005795 Golgi stack IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0045121 membrane raft IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004065 arylsulfatase activity IMP
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008449 N-acetylglucosamine-6-sulfatase activity IMP
 molecular_functionGO:0008484 sulfuric ester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr