ENSG00000196562


Homo sapiens

Features
Gene ID: ENSG00000196562
  
Biological name :SULF2
  
Synonyms : Q8IWU5 / SULF2 / sulfatase 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.12
Gene start: 47656348
Gene end: 47786616
  
Corresponding Affymetrix probe sets: 224724_at (Human Genome U133 Plus 2.0 Array)   233555_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000353007
Ensembl peptide - ENSP00000417894
Ensembl peptide - ENSP00000418290
Ensembl peptide - ENSP00000418442
Ensembl peptide - ENSP00000410026
NCBI entrez gene - 55959     See in Manteia.
OMIM - 610013
RefSeq - XM_017027955
RefSeq - XM_006723829
RefSeq - XM_006723830
RefSeq - XM_011528913
RefSeq - XM_011528914
RefSeq - XM_011528915
RefSeq - XM_011528916
RefSeq - NM_001161841
RefSeq - NM_018837
RefSeq - NM_198596
RefSeq - XM_005260458
RefSeq - XM_006723827
RefSeq - XM_006723828
RefSeq Peptide - NP_940998
RefSeq Peptide - NP_001155313
RefSeq Peptide - NP_061325
swissprot - H0Y872
swissprot - Q8IWU5
swissprot - B1AMP9
Ensembl - ENSG00000196562
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sulf2bENSDARG00000013838Danio rerio
 SULF2ENSGALG00000004593Gallus gallus
 Sulf2ENSMUSG00000006800Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SULF1 / Q8IWU6 / sulfatase 1ENSG0000013757365
GNS / P15586 / glucosamine (N-acetyl)-6-sulfataseENSG0000013567726


Protein motifs (from Interpro)
Interpro ID Name
 IPR000917  Sulfatase, N-terminal
 IPR014615  Extracellular sulfatase
 IPR017849  Alkaline phosphatase-like, alpha/beta/alpha
 IPR017850  Alkaline-phosphatase-like, core domain superfamily
 IPR024607  Sulfatase, conserved site
 IPR024609  Extracellular sulfatase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development ISS
 biological_processGO:0002063 chondrocyte development ISS
 biological_processGO:0003094 glomerular filtration ISS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production ISS
 biological_processGO:0014846 esophagus smooth muscle contraction ISS
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IDA
 biological_processGO:0030201 heparan sulfate proteoglycan metabolic process NAS
 biological_processGO:0032836 glomerular basement membrane development ISS
 biological_processGO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway ISS
 biological_processGO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway ISS
 biological_processGO:0048706 embryonic skeletal system development ISS
 biological_processGO:0051216 cartilage development ISS
 biological_processGO:0060348 bone development ISS
 biological_processGO:0060384 innervation ISS
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0097421 liver regeneration IEA
 biological_processGO:2000345 regulation of hepatocyte proliferation IEA
 cellular_componentGO:0005615 extracellular space NAS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005795 Golgi stack IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0009986 cell surface IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004065 arylsulfatase activity IMP
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008449 N-acetylglucosamine-6-sulfatase activity IMP
 molecular_functionGO:0008484 sulfuric ester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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